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Mouse Proinsulin,PI ELISA Kit,96t

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Product/service: Mouse Proinsulin,PI ELISA Kit 
Brand: Uscnlife 
Model: 96T 
Unit Price: 776 USD box  Inquiry 
Minimum quantity´╝Ü 1 (unit: box)  Place order 
Supply ability: 100 (unit: box)
Delievery time: Within 3 days upon receipt of payment
Valid through: Not expired
Last update on: 2011-01-27
View times: 1570
Company details
  • Wuhan EIAab Science Co., Ltd.
  • Contactchen lu       
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  • Location  China
  • Address  A1710 Guangguguoji,East Lake Hi-Tech Zone,Wuhan 430079,P. R. China
 
 
Product details

Intended use
This immunoassay kit allows for the in vitro quantitative determination of mouse Proinsulin, PI concentrations in serum, plasma and other biological fluids.
 
Introduction
Proinsulin is synthesized in the pancreatic beta cells as a 9390 mw polypeptide of 86 amino acids. Proinsulin is subsequently cleaved enzymatically, releasing insulin into the circulation along with a residual 3000 mw fragment called C-peptide, so-named because it connects the A and B chains of insulin within the proinsulin molecule.
Proinsulin, which has relatively low biological activity (approximately 10% of insulin potency), is the major storage form of insulin. Normally, only small amounts (~3% of the amount of insulin, on a molar basis) of proinsulin enter the circulation. Because the hepatic clearance of proinsulin is only 25% of insulin clearance, the half-life of proinsulin is two- to threefold longer and concentrations in the fasting state are approximately 10% to 15% of insulin concentrations.
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