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PARP Cleavage Detection Kit

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Product/service: PARP Cleavage Detection Kit 
Model: 512729-1KIT 
Size: 1 kit 
Unit Price: 449 USD   Inquiry 
Minimum quantity´╝Ü    
Supply ability:
Delievery time: Within days upon receipt of payment
Valid through: Not expired
Last update on: 2010-05-29
View times: 579
Company details
  • EMD Chemicals
  • ContactEMD Chemicals Inc.   
  •    Not registered
  • email  
  • Tel  
  • Location  USA
  • Address  Gibbstown, NJ 08027, USA
 
 
Product details

Assay range:

Assay time 5.5-6 h

Detection method Immunoblot

Form

Format Immunoblot

Kit contents:
An assay kit designed to detect poly(ADP-ribose) polymerase (PARP) cleavage by immunoblotting. PARP is an enzyme implicated in DNA damage and repair mechanisms. During apoptosis, PARP is cleaved by caspase-3. Cleavage of PARP from the native 116 kDa to 85 kDa is a hallmark of apoptosis. Each kit is provided with a highly specific rabbit polyclonal antibody that detects 116 kDa PARP and the 85 kDa apoptosis-related cleavage fragment from human, bovine, rat, and mouse.

References
Duriez, P.J., et al. 1997. Biochim. Biophys. Acta 1334, 65.Lazebnik, Y.A., et al. 1994. Nature 371, 346.Kaufman, S., et al. 1993. Cancer Research. 53, 3976.Lamarre, D., et al. 1988. Biochim. Biophys. Acta 950, 147.

Sample type Cell extracts

Sensitivity
http://eshop.emdchemicals.com/products/EMD_BIO-512729?WT.mc_id=EB000129

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