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Comparative Genomic Hybridization (CGH)

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CGH is a molecular cytogenetic method of screening a tumor for genetic changes. The alterations are classified as DNA gains and losses and reveal a characteristic pattern that includes mutations at chromosomal and subchromosomal levels. Laboratory of Automated Image Analysis, Institute of Pathology at Humboldt-University of Berlin. Content: CGH Images CGH Protocols CGH Online Tumor Database CGH Database (internal use only) CGH Related Method (LOH) CGH Publications CGH Links Color Figures of Publications Protocol include: Metaphase chromosome preparation DNA preparation by cryostom tissue dissection DNA labeling by nick translation Hybridization DNA detection Image capture Image analysis DAPI chromosome identification
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