vanin 1 (VNN1)
Name: VNN1
Description: vanin 1
Orgname: Homo sapiens
Status: 0
CurrentID: 0
Chromosome: 6
GeneticSource: genomic
MapLocation: 6q23-q24
OtherAliases: HDLCQ8, MGC116930, MGC116931, MGC116932, MGC116933, Tiff66
OtherDesignations: pantetheinase|vannin 1
NomenclatureSymbol: VNN1
NomenclatureName: vanin 1
NomenclatureStatus: Official
TaxID: 9606
Mim:
GenomicInfo:
GeneWeight: 3750
Summary: This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq]
ChrSort: 06
ChrStart: 133001996
UniProtein db: VNN1 UniProt protein knowledge database
Ensembl db: VNN1 Ensembl genome database
Complete information for VNN1 gene (protein-coding), vanin 1
Pantetheinase is an enzyme that in humans is encoded by the VNN1 gene.[1][2] ... This gene lies in close proximity to, and in same transcriptional orientation as ...
[VNN1] This gene product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. ...
AceView offers a comprehensive annotation of human, mouse and nematode genes reconstructed by co-alignment and clustering of all publicly available mRNAs and ESTs on ...
Rattus norvegicus. Vnn1 gene, Vnn1 microRNA and miRNA, Vnn1 transcript, and Vnn1 antibody; vanin 1; vanin 1 - Vnn1 RefGene Summary.
Abstract 367: Identification of the VNN1 Gene as a Novel CVD Risk Factor ... A gene of particular interest was VNN1 (vanin1) as its transcript levels ...
The researchers have also identified five genes that are causally downstream of VNN1 and thus ... VNN1 is a reasonable candidate gene for affecting HDL-C concentration. ...
We set out to identify novel genes associated with OA, concentrating ... VNN1 gene generates a recognition sequence for the endo- nuclease MnlI, this SNP was ...
One gene, VNN1, showed strong support for both cis-regulation (p=1.2×10-11) and correlation with HDL-C levels ... VNN1 expression levels were also significantly correlated with ...
Quantitative differences in gene expression are thought to contribute to phenotypic ... gene and association analysis of VNN1 promoter variants and VNN1 transcript abundance. ...
We identified Vnn1/Vnn3 as the likely candidates responsible for Char9. ... The Vnn1 and Vnn3 genes are adjacent to each other, are separated by 30 kb, and ...
GENE STRUCTURE Martin et al. (2001) reported the structural characterization of the human ... analysis of somatic cell hybrids, they localized the human VNN1 gene to 6q23-q24. ...
VNN1 is a member of the Vanin family of proteins which share extensive sequence ... The VNN1 gene lies in close proximity to, and in same transcriptional orientation as two ...
This gene encodes a member of the vanin family of proteins, which share extensive ... No NextBio groups were found for "VNN1". Be the first to start a group and share your ...
Species: Hu. This gene encodes a member of the vanin family of proteins, which share ... This gene encodes a member of the vanin family of proteins, which share extensive ...