TRAF family member-associated NFKB activator (TANK)

Name: TANK
Description: TRAF family member-associated NFKB activator
Orgname: Homo sapiens
Status: 0
CurrentID: 0
Chromosome: 2
GeneticSource: genomic
MapLocation: 2q24-q31
OtherAliases: I-TRAF, TRAF2
OtherDesignations: TRAF family member-associated NF-KAPPA-B activator|TRAF interacting protein TANK
NomenclatureSymbol: TANK
NomenclatureName: TRAF family member-associated NFKB activator
NomenclatureStatus: Official
TaxID: 9606
GeneWeight: 4622
Summary: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
ChrSort: 02
ChrStart: 161993465

UniProtein db: TANK UniProt protein knowledge database
Ensembl db: TANK Ensembl genome database

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