pseudouridylate synthase 10 (PUS10)

Name: PUS10
Description: pseudouridylate synthase 10
Orgname: Homo sapiens
Status: 0
CurrentID: 0
Chromosome: 2
GeneticSource: genomic
MapLocation: 2p16.1
OtherAliases: CCDC139, DOBI, FLJ32312, MGC126729, MGC126755
OtherDesignations: OTTHUMP00000201431|coiled-coil domain containing 139|pseudouridine synthase 10
NomenclatureSymbol: PUS10
NomenclatureName: pseudouridylate synthase 10
NomenclatureStatus: Official
TaxID: 9606
GeneWeight: 2756
Summary: Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM]
ChrSort: 02
ChrStart: 61167547

UniProtein db: PUS10 UniProt protein knowledge database
Ensembl db: PUS10 Ensembl genome database

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