6-pyruvoyltetrahydropterin synthase (PTS)

Name: PTS
Description: 6-pyruvoyltetrahydropterin synthase
Orgname: Homo sapiens
Status: 0
CurrentID: 0
Chromosome: 11
GeneticSource: genomic
MapLocation: 11q22.3-q23.3
OtherAliases: FLJ97081, PTPS
OtherDesignations: 6-pyruvoyl tetrahydrobiopterin synthase|PTP synthase
NomenclatureSymbol: PTS
NomenclatureName: 6-pyruvoyltetrahydropterin synthase
NomenclatureStatus: Official
TaxID: 9606
Mim:
GenomicInfo:
GeneWeight: 11812
Summary: The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq]
ChrSort: 11
ChrStart: 112097087

UniProtein db: PTS UniProt protein knowledge database
Ensembl db: PTS Ensembl genome database

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