protein kinase C, eta (PRKCH)
Name: PRKCH
Description: protein kinase C, eta
Orgname: Homo sapiens
Status: 0
CurrentID: 0
Chromosome: 14
GeneticSource: genomic
MapLocation: 14q22-q23
OtherAliases: MGC26269, MGC5363, PKC-L, PKCL, PRKCL, nPKC-eta
OtherDesignations: protein kinase C eta type
NomenclatureSymbol: PRKCH
NomenclatureName: protein kinase C, eta
NomenclatureStatus: Official
TaxID: 9606
Mim:
GenomicInfo:
GeneWeight: 16332
Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. [provided by RefSeq]
ChrSort: 14
ChrStart: 61788514
UniProtein db: PRKCH UniProt protein knowledge database
Ensembl db: PRKCH Ensembl genome database
Complete information for PRKCH gene (protein-coding), protein kinase C, eta
Protein kinase C eta type is an enzyme that in humans is encoded by the PRKCH gene.[1][2][3] ... The protein encoded by this gene is one of the PKC family members. ...
Genetic association between the PRKCH gene encoding protein kinase Ceta isozyme and ... RESULTS: Multiple SNPs in the PRKCH gene encoding the eta isozyme of protein ...
The protein encoded by this gene is one of the PKC family members. ... All SNPs in GeneID:5583 / PRKCH Gene [ ] Somatic Mutations in Cancer - Sanger's COSMIC ...
PRKCH Gene. in a French Caucasian Population with Rheumatoid Arthritis ... ( PRKCH) gene, which encodes the. η isozyme of protein kinase C (PKCη), is a good functional ...
Association between PRKCH gene polymorphisms and subcortical silent brain infarction. ... Department of Gene Diagnostics and Therapeutics, Research Institute, ...
involvement of PRKCH as a susceptibility gene for RA in. the Japanese population. ... PRKCH gene locus, all coding exons and a. 26-kb region in intron 2 ...
Browse > By Gene > PRKCH. PRKCH: protein kinase C, eta. Species: H. ... an email alert whenever other plasmids containing this gene become available, click here. ...
A method for testing whether or not a subject has a risk factor for arteriosclerotic disease, which uses the subject's PRKCH gene expression as an index. 5. ...
Browse > By Gene > Prkch. Prkch: protein kinase C, eta. Species: R. ... an email alert whenever other plasmids containing this gene become available, click here. ...
The data in COSMIC for PRKCH is from selected papers only and does not represent a wide survey of publications for this gene. Small Intragenic Mutation Summary ...
rs173686, in the CSPG2 gene, linked to intracranial aneurysm ... In Asian patients, two SNPs in the PRKCH gene have been linked to cerebral infartions: rs2230500, also known ...
Gene symbol. Chromosomal location. Gene name. Log in. PRKCH. 14q22-q23. Protein kinase C, eta ... Gene Symbol. Chromosomal location. Gene name. Log in. PRKCH. 14q22-q23 ...
SNP Nexus. Gene. PRKCH. Chromosome. 14. Orientation. minus. Position ... Asian populations, this SNP and a close neighbor also in PRKCH gene, rs3783799, ...
PRKCH. Species: Homo sapiens. Gene Definition: protein kinase C, eta. Gene Symbol: PRKCH ... The protein encoded by this gene is one of the PKC family members. ...