PARK2 co-regulated (PACRG)

Description: PARK2 co-regulated
Orgname: Homo sapiens
Status: 0
CurrentID: 0
Chromosome: 6
GeneticSource: genomic
MapLocation: 6q26
OtherAliases: hCG_1810756, FLJ32724, GLUP, HAK005771, PARK2CRG, RP3-495O10.2
OtherDesignations: OTTHUMP00000017729|molecular chaperone/chaperonin-binding protein|parkin co-regulated gene protein
NomenclatureSymbol: PACRG
NomenclatureName: PARK2 co-regulated
NomenclatureStatus: Official
TaxID: 9606
GeneWeight: 6038
Summary: This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson s disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson s disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
ChrSort: 06
ChrStart: 163148163

UniProtein db: PACRG UniProt protein knowledge database
Ensembl db: PACRG Ensembl genome database

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