megakaryoblastic leukemia (translocation) 1 (MKL1)

Name: MKL1
Description: megakaryoblastic leukemia (translocation) 1
Orgname: Homo sapiens
Status: 0
CurrentID: 0
Chromosome: 22
GeneticSource: genomic
MapLocation: 22q13
OtherAliases: RP5-1042K10.11, BSAC, MAL, MRTF-A
OtherDesignations: OTTHUMP00000199247|RBM15/MKL1 fusion|RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein|basic, SAP and coiled-coil domain|megakaryoblastic leukemia 1|megakaryoblastic leukemia 1 protein|megakaryocytic acute leukemia|myocardin-related transcription factor A
NomenclatureSymbol: MKL1
NomenclatureName: megakaryoblastic leukemia (translocation) 1
NomenclatureStatus: Official
TaxID: 9606
GeneWeight: 7861
Summary: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq]
ChrSort: 22
ChrStart: 40806291

UniProtein db: MKL1 UniProt protein knowledge database
Ensembl db: MKL1 Ensembl genome database

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