potassium channel, subfamily K, member 2 (KCNK2)
Name: KCNK2
Description: potassium channel, subfamily K, member 2
Orgname: Homo sapiens
Status: 0
CurrentID: 0
Chromosome: 1
GeneticSource: genomic
MapLocation: 1q41
OtherAliases: K2p2.1, MGC126742, MGC126744, TPKC1, TREK, TREK-1, TREK1, hTREK-1c, hTREK-1e
OtherDesignations: K2P2.1 potassium channel|TWIK-related potassium channel 1|potassium inwardly-rectifying channel, subfamily K, member 2|tandem-pore-domain potassium channel TREK-1|two-pore potassium channel 1
NomenclatureSymbol: KCNK2
NomenclatureName: potassium channel, subfamily K, member 2
NomenclatureStatus: Official
TaxID: 9606
Mim:
GenomicInfo:
GeneWeight: 8535
Summary: This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
ChrSort: 01
ChrStart: 215178884
UniProtein db: KCNK2 UniProt protein knowledge database
Ensembl db: KCNK2 Ensembl genome database
Complete information for KCNK2 gene (protein-coding), potassium channel, subfamily K, member 2
This gene encodes K2P2.1, one of the members of the two-pore-domain ... Mapping of human potassium channel genes TREK-1 (KCNK2) and TASK (KCNK3) to chromosomes ...
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twelve mammalian KCNK genes for 2 P domain potassium-selec ... The human KCNK2 gene encodes a 426-residue KCNK2 chan- nel subunit with two pore-forming P domains and four trans ...
SNP linked to Gene KCNK2(geneID:3776) Via Contig Annotation ... Total gene model (contig mRNA transcript): 3. mrna. transcript. protein. mrna orientation ...
Mapping of human potassium channel genes TREK-1 (KCNK2) and TASK (KCNK3) to chromosomes ... Institut de Pharmacologie Moléculaire et Cellulaire, CNRS, Valbonne, ...
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Over the past decade, a superfamily of KCNK genes encoding ... 2.1 subunits are predicted from the KCNK2 gene. sequence to have 426 amino acids and a ...
Support for the involvement of the KCNK2 gene in major depressive disorder and response ... Tryptophan hydroxylase 2 gene is associated with major depression and antidepressant ...
Disruption of the KCNK2 gene. ( A) Targeting vector (=loxp), native ... type (+/+), heterozygous (+/-) or homozygous (-/-) KCNK2 mice probed with P1 and ...
Brain Gene Expression Map for potassium channel, subfamily K, member 2. This is part of the Brain Gene Expression Map Project hosted at http://www.stjudebgem.org
Searched the available mouse databases for record(s) with gene name Kcnk2. ... ProbeSet/ILM7000497 [Kcnk2 on Chr 1 @ 191.031832 Mb]: potassium ...
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Figure 1 Disruption of the KCNK2 gene. ( A) Targeting vector (=loxp), native (WT) and ... Mean levels of gene expression, normalized to cyclophilin D, are ...
GENE FUNCTION Fink et al. (1996) found that K+ currents generated by expressed ... panel to map the human KCNK2 gene to chromosome 1q41 between markers WI5105 ...