FK506 binding protein 12-rapamycin associated protein 1 (FRAP1)

Name: MTOR
Description: mechanistic target of rapamycin (serine/threonine kinase)
Orgname: Homo sapiens
Status: 0
CurrentID: 0
Chromosome: 1
GeneticSource: genomic
MapLocation: 1p36.2
OtherAliases: FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
OtherDesignations: FK506 binding protein 12-rapamycin associated protein 1|FK506 binding protein 12-rapamycin associated protein 2|FKBP-rapamycin associated protein|FKBP12-rapamycin complex-associated protein 1|mammalian target of rapamycin|rapamycin and FKBP12 target 1|rapamycin associated protein FRAP2|rapamycin target protein
NomenclatureSymbol: MTOR
NomenclatureName: mechanistic target of rapamycin (serine/threonine kinase)
NomenclatureStatus: Official
TaxID: 9606
Mim:
GenomicInfo:
GeneWeight: 78895
Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq]
ChrSort: 01
ChrStart: 11166587

UniProtein db: FRAP1 UniProt protein knowledge database
Ensembl db: FRAP1 Ensembl genome database

Real-time quantitative PCR and RT-PCR primer sets for FRAP1
PATTYN, F., SPELEMAN, F., DE PAEPE A. & VANDESOMPELE, J. (2003). RTPrimerDB: the Real-Time PCR primer and probe database. Nucleic Acids Research, 31(1): 122-123.

Application: FRAP1 Gene Expression Quantification/Detection SYBR Green I PCR
Forward primer: AGGCCGCATTGTCTCTATCAA
Reverse primer: GCAGTAAATGCAGGTAGTCATCCA
Probe:
Amplicon:
Annealing temperature: 60

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