EPH receptor A2 (EPHA2)
Name: EPHA2
Description: EPH receptor A2
Orgname: Homo sapiens
Status: 0
CurrentID: 0
Chromosome: 1
GeneticSource: genomic
MapLocation: 1p36
OtherAliases: ARCC2, ECK
OtherDesignations: ephrin receptor EphA2|epithelial cell receptor protein tyrosine kinase|protein tyrosine kinase|soluble EPHA2 variant 1
NomenclatureSymbol: EPHA2
NomenclatureName: EPH receptor A2
NomenclatureStatus: Official
TaxID: 9606
Mim:
GenomicInfo:
GeneWeight: 24953
Summary: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. [provided by RefSeq]
ChrSort: 01
ChrStart: 16450831
UniProtein db: EPHA2 UniProt protein knowledge database
Ensembl db: EPHA2 Ensembl genome database
Complete information for EPHA2 gene (protein-coding), EPH receptor A2
OMIM: 176946 MGI: 95278 HomoloGene: 20929 GeneCards: EPHA2 Gene ... EPH receptor A2 (ephrin type-A receptor 2) is a protein that in humans is encoded by the EPHA2 gene.[1][2] ...
The EPHA2 gene is associated with cataracts linked to chromosome 1p ... A gene frequency of 0.001 and a penetrance of 100% were assumed for the disease locus. ...
Mouse Epha2 Chr4:140857155-140885299 bp, + strand has data for genome ... Mice homozygous for a gene trap allele exhibit increased incidence of chemically ...
The EPHA2 gene is associated with cataracts linked to chromosome 1p ... Here we identify a novel gene linked with a rare autosomal dominant form of ...
The EphA2 gene encodes an enzyme that plays a role in the repair of damaged proteins in ... Expression of the EphA2 gene decreases with age, which means damaged ...
The EphA2 gene encodes an enzyme that plays a role in the repair of damaged proteins in ... Expression of the EphA2 gene decreases with age, which means damaged ...
NewsRx is the leading source of news and information on Case Western Reserve University ... So his lab obtained a line of mice in which EphA2 gene had been deleted. ...
"It looks like we have found a gene in common with age-related cortical cataract, ... EPHA2 gene was present in families that tended to develop cortical ...
EphA2 gene silencing has been shown to result in antitumor efficacy. ... EphA2 targeted siRNA was tested in combination with either FAK or Src targeted ...
Addgene does not currently have plasmids containing this gene. ... made a plasmid containing this gene, please consider depositing it at Addgene. ...
Researchers in Cleveland have discovered the first gene associated with the formation of age-related cataracts. EphA2 encodes an enzyme that plays a role in the ...
Therapeutic EphA2 Gene Targeting In vivo Using Neutral Liposomal Small Interfering RNA Delivery ... When EphA2-targeting siRNA-DOPC was combined with paclitaxel, tumor ...
Therapeutic EphA2 Gene Targeting In vivo Using Neutral Liposomal Small Interfering RNA Delivery ... EphA2 is a tyrosine kinase receptor in the ephrin family that plays a ...
The EphA2 gene encodes an enzyme that plays a role in the repair of damaged proteins in ... Expression of the EphA2 gene decreases with age, which means damaged ...