acrosin (ACR)

Name: ACR
Description: acrosin
Orgname: Homo sapiens
Status: 0
CurrentID: 0
Chromosome: 22
GeneticSource: genomic
MapLocation: 22q13.33
OtherDesignations: preproacrosin|proacrosin
NomenclatureSymbol: ACR
NomenclatureName: acrosin
NomenclatureStatus: Official
TaxID: 9606
GeneWeight: 9651
Summary: Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. [provided by RefSeq]
ChrSort: 22
ChrStart: 51176651

UniProtein db: ACR UniProt protein knowledge database
Ensembl db: ACR Ensembl genome database

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