| |||||||||
| Login :: Register :: Search forums :: Top Users :: Reagent |
|
Position: Discussion forums > Bioscience biotechniques discussion forums > Molecular biology troubleshooting forum
|
MUTATION PREDICTION
Posted by: jobcn (IP Hidden, New member, 1)
Date: May 20, 2005 05:36AM
Can mutations be predicted?
If so, at what certainty lavel? Do you have any information of any method to do it, any publication or any group working on it? Thank you. Edited 1 times. Last edit at 05/21/05 08:17AM by jobcn.
Re: MUTATION PREDICTION
Posted by: femmeauburn (IP Hidden, Advanced member, 115)
Date: May 23, 2005 03:38PM
Yes some mutations can be predicated. Deleterious mutations have ben predicted by computer modeling. I am not certain at what level these models are reliable, as I just begin reading the literature a short while ago. Some of these models are Mendelian. Hope this helps! Try the publications below:
Deleterious mutation prediction in the secondary structure of RNAs Danny Barash* Nucleic Acids Research, 2003, Vol. 31, No. 22 6578-6584 Evaluation of structural and evolutionary contributions to deleterious mutation prediction Saunders, C. T., Baker, D. J Mol Biol 322: (4) 891-901 Sep 27 2002 Effect of Misreported Family History on Mendelian Mutation Prediction Models Hormuzd Katki Additional contact information Hormuzd Katki: Johns Hopkins Bloomberg School of Public Helath, Department of Biostatistics & Div. of Cancer Epidemiology & Genetics, National Cancer Institute No 1058, Johns Hopkins University Dept. of Biostatistics Working Paper Series from Berkeley Electronic Press
|
We are moving ... Please post to our new community forums
|
|
||||||||