Technique / Molecular Biology / RNAi siRNA gene silencing / siRNA design
Sfold web tool: siRNA, antisense, trans-cleaving ribozymes design tool
Sfold web tool: siRNA, antisense, trans-cleaving ribozymes design tool (archive)
Sfold predicts probable RNA secondary structures, assesses target accessibility, and provides tools for the rational design of RNA-targeting nucleic acids.
References:
Ding, Y., Chan, C.Y., and Lawrence, C.E. (2004) Sfold web server for statistical folding and rational design of nucleic acids. Nucleic Acids Res. 32 Web Server issue, W135-W141.
Ding, Y. and Lawrence, C.E. (2003) A statistical sampling algorithm for RNA secondary structure prediction. Nucleic Acids Res. 31, 7280-7301.
Ding, Y., and Lawrence, C.E. (2001) Statistical prediction of single-stranded regions in RNA secondary structure and application to predicting effective antisense target sites and beyond, Nucleic Acids Res. 29, 1034-1046.
Last update 30-May-2005, Rating Excellent! of 1 votes.
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By mohit nagori
on 30-May-2005
excellent |
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