Understanding DNA Methylation and Epigenetic Gene Silencing in Cancer

A open access book for continuing medical education (CME). The book can be downloaded as PDF file (1.5M). (Edited by Stephen Baylin, M.D.)

Recognize the distribution of CpG islands and gene promoters
* Describe the process of DNA methylation
* Explain what mediates DNA methylation
* Understand what couples DNA methylation to gene silencing
* Understand the relationship between histone modifications and gene expression
* Characterize our current ability to target DNA methylation and other gene silencing processes for therapeutic purposes

Last update 07-Mar-2006, Rating Fair of 2 votes.