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| Bioinformatics and computational biology involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. |
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Tutorials for Computational Biology and Genomics
recommended
review
Some valuable bioinformatics tutorial provided by Supercomuting Institute at University of Minnesota.
Bioinformatics Software Overview (Spring 2003)
BLAST tutorial from NCBI
EMBOSS tutorial from MRC
Microarray Microarray Analysis
GeneTraffic ( ...
Bioinformatics 2005 course lecture notes
new recommended
review
A 82 pages 2005 bioinformatics lecture note from Institute for Genomics and Bioinformatics, Christian Doppler Laboratory for Genomics and Bioinformatics, Graz University of Technology.
Content:
• Biological Databases: Information Retrieval
...
Bioinformatics tutorial online lecture
new
review
Online lecture on bioinformatics from Max Planck Institute.
Content:
Biological preliminaries
Introduction
References
Exercises
Answers
Analysis of individual sequences
Introduction
Helical wheels, amphipatic helices and coiled-coils ...
Introduction to bioinformatics
new
review
Introduction to bioinformatics, review written by Jacques Cohen.
Bioinformatics—An Introduction for Computer Scientists
Review by JACQUES COHEN
ACM Computing Surveys, Vol. 36, No. 2, June 2004, pp. 122–158.
Abstract. The article aims to introduce compu ...
RNA extraction / RNA isolation guidelines and protocols
new
review
RNA extraction from cells and tissues guideline:
- Avoid RNA degradation caused by RNase contamination.
- Increase RNA yield by thourough homogenizatio of tissue and cell samples.
- Increase RNA quality by proper precipitation of RNA and optimized RNA sto ...
Glossary of Bioinformatics Terms
new
review
A Quick Guide to Some Common Terms Used in Molecular Biology Databases. Definitions for some of the terms you may come across when using sequence databases, BLAST, and Protein Data Bank are provided below. (HGMIS)
General Terms from Sequence Databases and O ...
Computational Molecular Biology at NIH
recommended
site
Content
Sequence Analysis - tools at NIH and around the world
Documentation and Information - about sequence analysis tools and programs
Databases - for molecular biology
Molecular Biology Desk Reference - collection of basic information
...
Bioinformatics.org
new recommended
site
Official web site of Bioinformatics organization, inc.
Bioinformatics.org has over 12,000 members and 190 ongoing projects. ...
Bioinformatics Links Directory
recommended
site
A comprehensive collection of bioinformatics tools and databases by UBC Bioinformatics Centre.
The Bioinformatics Links Directory features curated links to molecular resources, tools and databases. All of the resources are free or available for a nominal fe ...
Bioinformatics programs and bioinformatics courses
new recommended
site
List of master and PhD degree programs in bioinformatics and computational biology. ...
Open Bioinformatics Foundation: Open Source Bioinformatics Projects
new recommended
site
Projects includes:
BioPerl
BioJava
BioPython
BioRuby
BioPipe
BioSQL / OBDA
MOBY
DAS
BioPathways†
EMBOSS†
...
biochemlinks - biology and chemistry links
site
BioChemLinks is a guide to the best biology and chemistry educational resources on the web. ...
LabOnWeb - a collection of gene discovery tools
site
Featured functions include InstantRACE analysis, Oligo minilibraries, PathoGenome analysis, 2Dgels analysis etc. ...
Bioinformatics courses at the Johns Hopkins University
new
site
Collection of bioinformatics courses from Johns Hopkins University. Bioinformatics courses include following courses with open-accessible pdf contents.
Bioinformatics courses:
- Statistics for Gene Expression
- Overview of Bioinformatics and Functional Ge ...
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Last update: 09-May-2008 06:34 am
Related new papers and reviews
Data analysis and bioinformatics tools for tandem mass spectrometry in proteomics. Physiol Genomics. 2008 Mar 14;33(1):18-25 Authors: Deutsch EW, Lam H, Aebersold R
Data processing is a central and critical component of a successful proteomics experiment, and is often the most time-consuming step. There have been considerable advances in the field of proteomics informatics in the past 5 years, spurred mainly by free and open-source software tools. Along with the gains afforded by new software, the benefits of making raw data and processed results freely available to the community in data repositories are finally in evidence. In this review, we provide an overview of the general analysis approaches, software tools, and repositories that are enabling successful proteomics research via tandem mass spectrometry.
Bioinformatics applications for pathway analysis of microarray data. Curr Opin Biotechnol. 2008 Feb;19(1):50-4 Authors: Werner T
Changes in transcript levels are assessed by microarray analysis on an individual basis, essentially resulting in long lists of genes that were found to have significantly changed transcript levels. However, in biology these changes do not occur as independent events as such lists suggest, but in a highly coordinated and interdependent manner. Understanding the biological meaning of the observed changes requires elucidating such biological interdependencies. The most common way to achieve this is to project the gene lists onto distinct biological processes often represented in the form of gene-ontology (GO) categories or metabolic and regulatory pathways as derived from literature analysis. This review focuses on different approaches and tools employed for this task, starting form GO-ranking methods, covering pathway mappings, finally converging on biological network analysis. A brief outlook of the application of such approaches to the newest microarray-based technologies (Chromatin-ImmunoPrecipitation, ChIP-on-chip) concludes the review.
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