Technique / Molecular Biology / PCR / Methylation specific PCR
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
protocol
Abstract: Precise mapping of DNA methylation patterns in CpG islands has become essential for understanding diverse biological processes such as the regulation of imprinted genes, X chromosome inactivation, and tumor suppressor gene silencing in human cancer. ...
(Reviews on methylation-specific PCR)
Derks S, Lentjes MH, Hellebrekers DM, de Bruine AP, Herman JG, van Engeland M.
Methylation-specific PCR unraveled.
Cell Oncol. 2004;26(5-6):291-9.
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