Technique / Genetics / Genotyping / Single Nucleotide Polymorphism SNP analysis


NCBI human SNP database recommended database
In collaboration with the National Human Genome Research Institute, The National Center for Biotechnology Information has established the dbSNP database to serve as a central repository for both single base nucleotide subsitutions and short deletion and insert ...

Single Nucleotide Polymorphisms for Biomedical Research new recommended database
The SNP Consortium: Single Nucleotide Polymorphisms for Biomedical Research. Single nucleotide polymorphisms (SNPs) are common DNA sequence variations among individuals. They promise to significantly advance our ability to understand and treat human disease ...

SNPbrowser Software for SNPs studies recommended database
A free downloadable SNPs software from Applied Biosystems. Features: 1. Browse the Human Genome for SNPs 2. Help You Select Markers. Identify putative tagging SNPs. 3. Easily Order and Design SNP Genotyping Assays Online ...

SNPview: SNPs, SSLPs, Alleles and Haplotypes database
The viewer allows comparing the distribution of the SNPs and SSLPs, alleles and derived haplotype blocks in different regions of the mouse genome. Several different views are available for each chromosome: a chromatogram-style view of validated SNPs, major and ...

SNPseek - Retrieval and Analysis of Functionally Relevant SNPs new database
SNPseek, a database of putatively functional human SNPs, integrated with extensive minor allele frequency data and genomic annotations. (Washington University School of Medicine, SNP research facility) ...

SNP LIMS - Laboratory Information Management System new software
Small-scale SNP detection experiments generate massive amounts of data, much of which can potentially be captured and analyzed in an automated fashion. However, no current software tool exists to comprehensively capture and m anage SNP discovery data. Instead, ...


SNP analysis methods
(Biowww bookstore)
Single nucleotide polymorphism analysis (SNP analysis) is an important technique for detecting genetic differences among individuals. SNP commonly refer to single base variations in DNA sequence among individuals. SNP alleles are useful marker for disease and in some cases SNPs contribute disease development. Nonsynonymous SNP can cause amino acid difference wherase SNPs in promoter region can affect the protein expression regulation at transcriptional level. Techniques to detect and analyze SNPs include Denaturing High-Performance Liquid Chromatography, SSCP for SNP Detection and Allele Frequency
Determination, CSGE (conformation-sensitive gel electrophoresis), solid-phase chemical cleavage, DNA sequencing, molecular beacons genotyping, 5'-nuclease reaction SNP genotyping, minisequencing primer SNP genotyping, solid-phase minisequencing for SNP quantitative analysis, homogeneous primer extension assay, pyrosequencing for SNP genotyping, SNP genotyping using homogeneous allele-specific PCR, oligonucleotide ligation assay, and MALDI-TOF mass spectrometry SNP genotyping etc.

For complete references, please click the Related Books tab on the right.

SNP Genotyping Assays Protocol

SNP genotyping introduction

SNP resources at Washington University


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