Books on 'apoptosis'
Total books: 368 Page 8 of 37
publisher: Biotech Patent News, published: 2001-08-01
Product Description
This digital document is an article from BIOTECH Patent News, published by Biotech Patent News on August 1, 2001. The length of the article is 470 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.Citation DetailsTitle: Idun expands apoptosis patent portfolio.(Brief Article)Publication: BIOTECH Patent News (Newsletter)Date: August 1, 2001Publisher: Biotech Patent NewsVolume: 15 Issue: 8 Page: NAArticle Type: Brief ArticleDistributed by Thomson Gale
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publisher: W. B. Saunders, published: 2001
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by: Philip J. Barr, Michael C. Kiefer
publisher: Chemical Institute of Canada, published: 1995-11-01
Product Description
This digital document is an article from Canadian Chemical News, published by Chemical Institute of Canada on November 1, 1995. The length of the article is 785 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.Citation DetailsTitle: Bak, the Bcl-2-homologous antagonist/killer, a critical modulator of apoptosis in human disease.Author: Philip J. BarrPublication: Canadian Chemical News (Magazine/Journal)Date: November 1, 1995Publisher: Chemical Institute of CanadaVolume: v47 Issue: n10 Page: p22(2)Distributed by Thomson Gale
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publisher: Springer, published: 1998-12-11
ISBN: 3540646248
sales rank: 3544648
Product Description
This volume deals with many of the recent advances made in uncovering the molecular and cellular basis of apoptosis and elaborates on how this accumulating knowledge is helping us to understand the significance of apoptosis in pathogenesis of diseases arising from inappropriate cell death. Further, mechanistic aspects of cell death and role of apoptosis in disease is covered.
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by: D. Hughes, David Hughes, H. Mehmet
publisher: BIOS Scientific Publ, published: 2002-07-19
ISBN: 1859961932
sales rank: 3465507
Product Description
Cell Proliferation and Apoptosis is a detailed practical guide to cell proliferation and cell death detection methods, taking a novel approach that combines both areas and allows important comparisons to be made. Topics covered encompass all aspects of tissue handling from collection, storage, fixation and processing, through to locating and quantifying cells in different stages of the cell cycle. Also included in the book are: sample types and their preparation, in vivo studies, identification and confirmation of apoptosis, and accounts of typical applications of the methods described. Cell Proliferation and Apoptosis is an essential and comprehensive practical guide to these important and expanding research techniques.
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by: Edited by Benjamin Bonavida
publisher: Transworld Research Network, published: 2006-01-01
ISBN: 8178952424
Product Description
This volume has been conceived to provide different approaches used to overcome resistance through the use of chemo or immunosensitizing agents, used in combination with cytotoxic drugs. This volume has been divided arbitrarily into two sections, namely, chemosensitization and immunosensitization. Chemosensitization refers to the use of sensitizing agents that can reverse resistance to chemotherapeutic drugs. Immunosensitization refers to agents that can sensitize tumor cells through cytotoxic mechanisms mediated by host immune cells and/or corresponding cytotoxic factors. The authors in this volume are well established investigators in the field of sensitization and represent expertise in novel approaches used for sensitization. This volume is by no means all inclusive and primarily represents some examples that have been selected for reference.
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by: E.A. Stokes, W. Lonergan, L.P. Weber, D.M. Janz, P
publisher: Elsevier, published: 2004-06-01
Product Description
This digital document is a journal article from Comparative Biochemistry and Physiology, Part C, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.Description: Endocrine disrupting compounds (EDCs), especially those that are estrogenic, are an issue of growing concern because they may ultimately adversely affect wildlife survival. 17-@b-Estradiol and its synthetic counterpart, 17-@a-ethinylestradiol, two common EDCs, are associated with intersex conditions and impaired male reproductive behavior in fish. Male and female Japanese medaka (Oryzias latipes) were exposed to 10 ng/l ethinylestradiol for 6 months. Using terminal dideoxynucleotidyl-mediated dUTP nick end-labeling (TUNEL) to quantitate cell death, we found that ethinylestradiol-exposed males had significantly fewer apoptotic cells in the forebrain compared to untreated males and exposed females. Our results show that the effects of ethinylestradiol exposure are highly variable among individuals of the same species and even within tissues of the same individual. Thus, when examining the effects of EDCs on natural populations, data from a variety of tissues should be examined and the interpretation of any effects should include consideration of tissue-specific processes.
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by: Yong Fu
publisher: VDM Verlag Dr. Müller, published: 2009-03-09
ISBN: 3639131800
Product Description
GRP78, a molecular chaperone at the endoplasmic reticulum (ER), is highly elevated in malignant tumors and correlates with severe pathological grade and poor prognosis. GRP78 affects apoptosis by regulating ER Ca2+ signaling and unfolded protein response, but whether other mechanisms exist remains unknown. Searching for novel partners interacting with GRP78 at the ER, we discovered that BIK selectively forms a complex with GRP78. GRP78 overexpression decreases apoptosis induced by BIK. For breast cancer cells that require BIK to mediate estrogen starvation-induced apoptosis, GRP78 overexpression inhibits estrogen starvation-induced BAX activation, mitochondrial permeability transition, and consequent apoptosis. Further, knockdown of endogenous GRP78 by siRNA sensitizes those cells to estrogen starvation. This effect was substantially reduced when BIK level was reduced by siRNA. Additionally, an in vivo study in a Pten conditional knockout mouse model of prostate cancer reveals that homozygous deletion of Grp78 blocks prostate cancer progression initiated by Pten nullification. Our results provide evidences that GRP78 is critical in apoptosis regulation and cancer progression.
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publisher: Springer, published: 2009-05-11
ISBN: 1402098723
Product Description
Apoptosis: Involvement of Oxidative Stress and Intracellular Ca2+ Homeostasis, presents a concise synthesis of the current knowledge and recent advances in the mechanisms of apoptosis in different cells and the role of oxidative stress and Ca2+ signalling. Particular attention is given to the different features of apoptosis in distinct cell types, ranging from hepatocytes to cardiovascular and blood cells, nervous cells or spermatozoa. Cutting-edge and user-friendly, this volume serves as a comprehensive resource for those interested in the fascinating biological processes associated to programmed cell death or apoptosis. The book is divided in two major chapter sections: general mechanisms of the apoptotic pathways and the role of oxidative stress and intracellular Ca2+ homeostasis and a more specific section dedicated to the specificities of apoptosis in a number of excitable and non-excitable cells. All of the contributions are from specialists in the field and the reviews presented, systemically examine the most exciting and innovative aspects of the apoptotic pathways in their particular areas of expertise.
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by: Sara Yasemin Demiroglu
publisher: Suedwestdeutscher Verlag fuer Hochschulschriften, published: 2010-01-14
ISBN: 3838111702
Product Description
Intracellular heat shock protein 70 (HSP70) belongs to the stress response system and can protect cells from different apoptotic stimuli. Extracellular HSP70 on the other hand can activate cells of the innate and adaptive immune system. Acute overexpression of intracellular HSP70 could even increase the susceptibility of melanoma cells to cytotoxic T-lymphocytes (CTLs) that use the granule-exocytosis pathway for killing (Dressel et al. 1999). To decipher the molecular pathway of this increased susceptibility to CTLs, the effect of the acute overexpression of HSP70 on gene expression was analysed in cells, in which Hsp70 is under the control of a tetracycline-inducible promoter. To reduce the complexity of CTL-induced apoptosis, further experiments were performed with granzyme (Gr)B, a component of the cytotoxic granules of CTLs and NK cells, that has been shown to interact with HSP70. Heparan sulphates on the other hand are involved in GrB-binding to target cells of CTLs and are modified in their sulphation pattern by sulphatases 1 and 2. The role of HSP70 and sulphatases 1 and 2 in GrB-induced apoptosis is analysed.
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cell culture, methods in cell biology, apoptosis, cell cycle, mitosis, signal transduction, receptor, mitochondria, ribosome, stem cell, flow cytometry
Total 368 books of 37 pages