Related books on 'apoptosis'
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publisher: Springer, published: 2001-12-07 ASIN: 4431703233 EAN: 9784431703235 sales rank: 4536367 Yamaguchi Univ., Japan. Proceedings of the 12th symposium held on December 9 and 10, 2000, at the ANA Hotel, Ube, Japan. Deals with the understanding of the pathophysiology of intractable liver disease. DNLM: Hepatocytes--cytology--Congresses. |
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publisher: Wiley-Liss, published: 2003-12-22 ASIN: 0471219479 EAN: 9780471219477 sales rank: 2736449 Cell death is fast becoming one of the most dynamic areas of biological research-involving as it does the study of apoptosis and programmed cell death and the role these phenomena play in development and homeostasis on the one hand, and aging and disease on the other. The profound implications for medicine and agriculture from the manipulation of these processes have spawned a deluge of research papers, articles, approaches, and methods-making it difficult for scientists to get an overview of the field. When Cells Die II: A Comprehensive Evaluation of Apoptosis and Programmed Cell Death offers the most thorough, cutting-edge coverage of this field since publication of the acclaimed first edition. Leading international researchers present an up-to-date yet accessible survey ranging from the history of cell death science to its modern methodology. Extensively revised to include major advances in research, this new edition features relevant discussion of: * The impact of genomics and proteomics * Gene therapy and pharmacogenetics * The role of mitochondria * Caspase-independent and non-apoptotic cell death * Evolution of mechanisms With the manipulation of programmed cell death in clinical situations now in the foreseeable future, When Cells Die II also addresses the role of apoptosis in specific organ systems-the immune system, nervous system, and gastrointestinal tract-as well as different disease states, including viral infection, cancer, and myocardial infarct. Expertly edited to provide detailed cross-referencing, consistency of style, and a logical progression of topics, When Cells Die II is the definitive resource for understanding current cell death science. It will prove an invaluable text for advanced undergraduate, graduate, and medical students, postdoctoral fellows, scientists, and clinicians in cell biology, immunology, developmental biology, neuroscience, and cancer research. |
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publisher: Springer, published: 1999-04-28 ASIN: 3540650237 EAN: 9783540650232 sales rank: 7680601 The maturation phenomenon refers to postischemic changes that develop hours or days following an ischemic insult. The delayed neuronal death of CA1 pyramidical cells of the hippocampus is a classic example. The report of the phenomenon has boosted research in this field, as it became evident that ischemic damage is not a sudden event but a process potentially susceptible to therapeutic intervention. In September 1990, the first international symposium on "Maturation Phenomenon in Cerebral Ischemia" was held in Tokyo. The second symposium was organized in Tokyo in March/April 1996. Since then, new developments have rapidly delivered information about the molecular nature and dynamics of mechanisms concerning cell death and recovery. This book contains the presentations of the 3rd international symposium held in Pozilly/Italy in April 1998. It outlines the present status of the investigation and provides further stimulation for research in this field. |
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by: Toshio Hata publisher: University of Rochester Press, published: 1999-11-15 ASIN: 158046064X EAN: 9781580460644 sales rank: 4816700 This work, the 13th Volume of Trophoblast Research series, comprises collected papers presented at the 4th Conference of the International Federation of Placenta Association in conjunction with the 6th Japan Placenta Association and the 16th Annual Meeting of Trophoblastic Disease (Japan), held at the Tokyo Medical Center in 1998. The papers all relate to the general theme: 'The Control Mechanisms of Proliferation and Invasive Function for Placental Trophoblastic Cells.' |
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publisher: Springer Berlin Heidelberg, published: 2010-01-14 ASIN: 3642061923 EAN: 9783642061929 This mechanism of programmed cell death plays an important role in normal development and control of cell numbers in mature animals. Initiation of the apoptotic process can come from external or internal stimuli and is highly regulated both by molecules that facilitate and by molecules that inhibit the process. I can be envisioned that apoptosis as a response to an intracellular pathogen is a useful way for the host to eliminate infected cells, decreasing the likelihood of spread of the infection to neighboring cells and preventing pathogen persistence. Alternatively, the apoptotic response may be a major mechanisms by which the host is harmed by a pathogen. |
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publisher: Taylor & Francis, published: 1996-03-12 ASIN: 0748404449 EAN: 9780748404445 sales rank: 4429363 In apoptosis in the mammalian system, cells have a finite life - they develop, are used and then die. Cancer cells escape this programmed routine but, from an understanding of apoptosis, they can be programmed to die. This book addresses the |
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publisher: Springer, published: 2008-03-27 ASIN: 3540742638 EAN: 9783540742630 sales rank: 5598887 The interactions between viruses and the cells they infect include the virus control of cellular functions to their advantage. The cell counteracts with a defensive immune system and stress responses. Both sides of this struggle include modifications in the cell death program that will be crucial for the infection outcome. In this book, molecular pathways regulated by viral genes and their role in the pathogenesis of infection are analysed in different viral models. It also includes a didactic update of known signaling pathways in apoptosis and their role in normal and infected cells. Special emphasis was given to molecular pathways underlying viral transformation and oncogenesis and to the perspectives in cancer gene therapy. Particular cell types in apoptosis such as neuronal cells and lymphoid cell death are also emphasized. This book is designed to give an in-depth update of viral gene interaction with regulation pathways in apoptosis for scientists and researchers in the fields of molecular biology, virology, cell biology, oncology, and neurobiology. |
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publisher: Springer, published: 2002-05-31 ASIN: 0306467828 EAN: 9780306467820 sales rank: 5858602 The last few years have witnessed an explosion of both interest and knowledge about apoptosis, the process by which a cell actively commits suicide. It is now well recognised that apoptosis is essential in many aspects of normal development and is required for maintaining tissue homeostasis. The molecular mechanisms of apoptosis are presently unknown and the subject of focused research effort. It is clear that cell membrane structure and properties play an early part in the induction process. There is increasing evidence that the arrangement of polar lipids in the membrane lipid matrix is an important factor coupled with the homeostatic mechanisms responsible for preserving membrane lipid involved, possibly as a direct consequence of disturbances in the lipid bilayer matrix. The purpose of this volume is to examine the involvement of membrane lipids in early events of apoptosis. In particular, the role of phospholipids in mitochondrial permeability, membrane lipid asymmetry, and sphingolipid and phospholipid signalling processes in early apoptotic events are reviewed by current researchers in these fields. |
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publisher: Springer Netherlands, published: 2009-12-28 ASIN: 9048166152 EAN: 9789048166152 Integrating advances in molecular biology into bioprocesses presents a continuous challenge to scientists and bioengineers. This series is conceived to help meet this challenge. It examines and assesses the feasibility of new approaches for the modification of cellular function such as gene expression, protein processing, secretion, glycosylation, immortalisation, proliferation, and apoptosis as well as the systematic study of the metabolic genotype--phenotype relationship. The series provides detailed coverage of the methodology for improving cellular properties of cells used in the production of biopharmaceuticals, gene and cell therapies and tissue engineering. It also seeks to explain the cellular mechanisms underlying in vitro physiological activity and productivity. This volume, which is based on presentations at the `European Workshop on Animal Cell Engineering' held in Costa Brava, Spain, contains a collection of chapters relating to cellular function and modification by leading authorities in several different areas of basic research and the biopharmaceutical industry. |
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publisher: Springer, published: 1997-12-04 ASIN: 3540634177 EAN: 9783540634171 sales rank: 5448840 This volume in the series "Advances in Biochemical Engineering/Biotechnology" focuses on bioprocess and algae reactor technology and apoptosis. All aspects of this interdisciplinary technology, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science are treated. |