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 | | By: Jon F. Wilkins ISBN: 0387775757 Publisher: Springer Release Date: 31 January, 2008 Bioscience book rank: 1014603
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 | | By: Eric H. Davidson ISBN: 0122053516 Publisher: Academic Press Release Date: 15 February, 2001 Bioscience book rank: 827639
| This is a very intersting book on an amazing topic which is straightforward enough for an interested educted layman to understand. But unfortunately it is a wierd mix of chatty remarks and pointlessly obstruse passages that read like letters to Nature.
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<br />The very worst thing is the illustrations and blurbs. The design is so bad that it really is hilarious at times. Sometimes the blurbs are so long they are spread onto the next page. The contain three or four different fonts in the same sentence. The sources of the information are pointless mixed with non-technical information about the content...
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<br />There is no logic in the way "subillustrations" are combined to illustrations. (Why do they insist on subillustrations at all? Why not make separate illustration?) They are just slapped together any old way. Sometime there are additional frams, sometimes not. Even the numbering convention varies. The order that the subillustration appear in the illustrations is also random.
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<br />The book is almost impossible to read. It needs to go back to the publisher and be totally reorganized for readability.
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<br />What a pity. The content is actually fascinating.
This book is complementary too, but on a more advanced level than Sean Carroll's From DNA To Diversity, which I strongly recommend as a great intro book to evo-devo. Davidson's book is tough going in places, which is why I gave it one star off, but the material is in fairness quite complex. He emphasizes the role of cis-regulatory sequences in genes and the structure of the systems that regulate gene expression in development and evolution in some detail. It becomes clear how minor mutations in the regulatory part of a gene can transform how it is expressed, and why the importance for evolution in mutations in gene expression is clearly much greater than for mutations in the protein coding sequence. His explanation for what is responsible for the incredible homologies in, for example, the pax 6 gene that regulates eye development across phyla is very illuminating. A must read for anybody interested in the molecular basis for development and evolution.
Genomic Regulatory Systems : development and evolution, by<br>Eric Davidson<p>The book is about how the genome actually works in [embryo?] development.<br>It is a beautiful book with many attractive illustrations.<br>The book's introductory material and<br>that of each chapter is clear and interesting.<br>I enjoyed about 3 valuable hours with this book<br>before getting lost because of my inadequate background (nonbio major).<br>He gives 4 reasons why this field has been so exciting over the past decade:<br>(1) We can now bring regulatory hard wiring at<br>the DNA nucleotide level into concise functional focus,<br>(2) We now have the full DNA sequence,<br>(3) Good minds from evolution and from development have converged,<br>(4) A lot of confusion in molecular phylogeny has been cleared up.<p>The book is mostly about bilaterians.<br>The size of the genome within a clade [some very similar critters]<br>can vary by a factor of ten whereas<br>the variation in protein coding (mRNA) is much smaller.<br>Amniotes [embryo in sac] have 4 hox clusters on 4 chromosomes.<br>There are remarkable examples of diverse usage of similar genes<br>of diverse organisms.<br>I don't think he defines the difference between cis- regulatory elements<br>[within the chromosome] and trans- [across chromosomes] so I needed<br>to do some guessing or find some other references.<br>Next time I take another look at this book,<br>I'll probably restart back about page 9.<br>I noticed on page 110 on the morphogenesis of heart parts<br>that different genes were identified for right and left sides<br>of the heart -- a matter of interest to me as my apparantly healthy 25 year old son ...died suddenly and unexpectedly<br>of natural causes,***many tears***, presumably a heart attack.<br>Perhaps the next decade or two will bring life-saving diagnostics. |
 | | By: Rajeev Varshney, Roberto Tuberosa ISBN: 140206294X Publisher: Springer Release Date: 06 February, 2008 Bioscience book rank: 1006900
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 | | By: James F. Hancock ISBN: 1402069065 Publisher: Springer Release Date: 01 March, 2008 Bioscience book rank: 1107839
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 | | By: Charles R. Cantor, Cassandra L. Smith ISBN: 0471599085 Publisher: Wiley-Interscience Release Date: 02 February, 1999 Bioscience book rank: 975315
| So far I heard that this is the one of the best book containing all informations and instructions about genome project. I love to review this book throgh e-mail.<br>I can't afford myself to buy this book. but so far i can say if it is really very much helpful to me i recommend evybody of my class (MSC Bioinformatics) to go for buying that book.<p>with thanks
as good as GENE VI by Lewis |
 | | By: James R. Brown ISBN: 0849392160 Publisher: CRC Release Date: 03 December, 2007 Bioscience book rank: 352847
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![]() | | By: C. Cristofre Martin ISBN: 1588297772 Publisher: Humana Press Release Date: 18 January, 2008 Bioscience book rank: 1026963
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 | | By: José Marín-García, M.J. Goldenthal, G.W. Moe ISBN: 0387740716 Publisher: Springer Release Date: 19 December, 2007 Bioscience book rank: 1058459
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 | | By: Laura A Katz, Debashish Bhattacharya ISBN: 0198569742 Publisher: Oxford University Press, USA Release Date: 09 November, 2006 Bioscience book rank: 980317
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 | | By: Karen D., Ed. Drickamer ISBN: 1855781549 Publisher: Portland Press, Ltd. Release Date: 2002 Bioscience book rank: 1081203
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Related books in this category:
methods in molecular biology, PCR, RT-PCR and real-time quantitative PCR, Differential Display, recombinant DNA, gene therapy, virus protocols, lentivirus methods, gene targeting, mouse knock-out and knock-in, transgenic technology, phenotyping, gene delivery and transfer, transcriptional regulation, RNA methods, RNA Polymerase, gene expression, protein translation regulation, protein kinase, protein phosphorylation, genomics, genomics methods, epigenetics, DNA methylation, DNA sequencing, RNA interference, microarray Main book index: all categories
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