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By: James F. Jekel, David L. Katz, Joann G. Elmore ISBN: 0721690793 Publisher: Saunders Release Date: 15 September, 2001 Bioscience book rank: 585491
| Worth its weight in gold. Covers the principles of every subject area required for board certification by the American Board of Preventive Medicine. Includes numerous lists, tables, charts, and a full set of referenced questions and answers. Downright poignant considering the precipitous decline in America's public health and preventive medicine infrastructure since the day George W. Bush assumed office.
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<br />Mark Gary Blumenthal, MD, MPH
This is a useful study guide and reference tool for anyone who is starting in epidemiology. It gives a great overview on study designs, statistics, and a great deal of other useful information for creating, implementing and evaluating a study. I have found it extremely useful in both my studies and in the implementation of studies. I would recommend this book as a study tool in any epidemiology course! |
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By: Shein-Chung Chow ISBN: 1584889055 Publisher: Chapman & Hall/CRC Release Date: 30 May, 2007 Bioscience book rank: 605922
| When the expiration date on a drug passes, the pharmacist must destroy the items that exceed their shelf life. In a clinical trial, drugs stored for use in the trial can exceed their self life and then must be destroyed. Since the late 1980s the FDA requires that stability testing be conducted to establish the self life of a drug. Products discovered to be ubnstable have been taken off the market. Therefore, stability testing is an important part of the early phase statistical analysis of a new drug. Yet in my nearly five years of experience as a clinical trials statistician in the pharmaceutical industry I was only once (and only just recently) confronted with the issue. We had a drug that started phase III but in the course of the trial some of the stored samples decame unstable and the trial was put on hold. As the manufacturer of the product we had make changes to ensure that moisture did not get into the vials to ruin the mixture. We were motivated to fix the problem quickly and get the trial restarted. However bioavailability and stability needed to be reestablished. I learned that we used very rudimentary and in accurate tools to estimate the stability from the test batches. This meant the during the trial we could only claim a minimal shelf-life and the drug could be wasted because of the need to destroy it before it "really" expired. So it was with pleasure and excitement that I bought this book.
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<br />Professor Chow has authored, co-authored and edited books on every aspect of the statistics of drug development. As usual he is very thorough in his presentation of the topic, the FDA and ICH rules and guidelines and the development of the various options for statistical analysis. This is another in the long series of publications by Dr. Chow and his colleagues. He is always at the forefront being the first or one of the first to present new statistical methods or applications to the biopharmaceutical community. A book that is a must for the bookshelf of any biopharnaceutical statistician! |
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By: Peter J., PhD Fos, David J, MHA Fine, Brian W. Amy, Miguel A. Zúniga ISBN: 0787978914 Publisher: Jossey-Bass Release Date: 08 June, 2005 Bioscience book rank: 272085
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By: Lemuel A. Moyé ISBN: 1584887249 Publisher: Chapman & Hall/CRC Release Date: 27 July, 2007 Bioscience book rank: 926756
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By: Noel S. Weiss ISBN: 019530523X Publisher: Oxford University Press, USA Release Date: 01 June, 2006 Bioscience book rank: 855377
| This book was a reference for the course "Clinical Epidemiology" taught by Noel Weiss. I originally borrowed this from the library, but after completing the course, I have realized this is a book I want to have onhand forever. Clear, concise with excellent examples. The chapters excellently describe the subtle issues with RCTs, case control, cohort studies and those designed to measure safety. |
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By: Shein-Chung Chow, Jen-pei Liu ISBN: 0824775724 Publisher: CRC Release Date: 24 November, 1999 Bioscience book rank: 655855
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By: Robert Nordness ISBN: 0323034063 Publisher: Mosby Release Date: 21 October, 2005 Bioscience book rank: 524527
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By: Michael R. Chernick, Robert H. Friis ISBN: 047141137X Publisher: Wiley-Interscience Release Date: 17 March, 2003 Bioscience book rank: 190322
| This is my husband's second book. It came out based on a course he taught to undergraduate health science majors at Cal State Long Beach. He taught it successfully twice. It is a clear introduction for the novice like me and has a good set of exercises and references for further reading. Mike works in the pharmaceutical industry and previously in medical devices. He brings his experience to bear on the examples and to motive the students to see the real value of statistics to their future profession. His coauthor also taught the course at cal State Long Beach and provided many of the exercises and some of the applications particularly in the area of epidemiology which is his specialty. The book has been slow to be adopted in some classrooms because of thre novel introduction of bootstrap a technique that many instructors are not familiar with. But if you look at the review in JASA you will see that this is a strength of the book and is presented simply and only for the most basic bootstrap techniques and applications. It is worth the effort to learn these techniques and to choose this book over some competitors that just do the standard things and look exactly like each other.
Biostatistics textbooks usually either concentrate on the math or the explanations, and end up giving an unbalanced idea of the subject at hand.
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<br />Texts that choose to have both as different modules, are generally large (therefore more or less reference), expensive and at times incoherent.
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<br />I have come across a variety of texts dealing with the subject, from the popular Motulsky's book, Rosner, Dytham and even most of the Wiley series. I have found that this is one of those very few texts available that has a balanced explanation of stat with "the english of it" and "the maths of it".
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<br />In general the book follows the same sequence as standard biostatistics courses offered at second year of university. However it assumes the reader knows very little, at that same token the book is not written in a conderscending manner.
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<br />It is so well written that it can probably appeal to most readerships (undergraduate that is). It is not only an excellant primer but also a workable textbook.
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By: Adam Brochert ISBN: 1560535768 Publisher: Hanley & Belfus Release Date: 11 April, 2003 Bioscience book rank: 946223
| Know these Vignettes! Nothing more to say. They will be tested over. Period :) Terribly boring subject, but points are points.
Using this review source helped me sleep better before the exam, because I felt ready for the "case-based" style of the boards that everyone kept telling me about. This is a great series, but I don't think it should be used as a stand alone review source. Case-based coverage of topics means that some topics are missed/not covered. However, the topics covered by this volume were very high yield for my exam. Definitely worth the money!
Not a big fan of behavioral science, but this book makes it bearable by focusing on what you'll be tested on and helping you distinguish similar conditions from each other. Good biostatistics section also included. Great information and great figures to help you understand the info. Strongly recommend - the rest of the series is also outstanding. |
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By: R. A. De Fronzo, Ele Ferrannini, Harry Keen, Paul Zimmet ISBN: 0471486558 Publisher: Wiley Release Date: 25 June, 2004 Bioscience book rank: 925480
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