epigenetics|chromatin books


	Annual Plant Reviews, Plant Epigenetics (Volume 19) publisher: Wiley-Blackwell, published: 2005-10-01 ISBN: 1405129778 sales rank: 1429519 Product Description With the discovery of RNAi pathways and the histone code, epigenetics has become a popular and fast evolving research topic. Plant science has made a number of elementary contributions to this field, and the common elements of epigenetic systems have linked research groups interested in plant, fungal and animal systems.This volume provides a comprehensive overview epigenetic mechanisms and biological processes in plants, illustrating the wider relevance of this research to work in other plant science areas and on non-plant systems. It discusses recent advances in our knowledge of basic mechanisms and molecular components that control transcriptional and post-transcriptional silencing, an understanding of which is essential for plant researchers who use transgenic lines for stable expression of a recombinant construct or for targeted inactivation of an endogenous gene. These aspects should be of special interest to the agricultural industry.The volume illustrates! the relevance of epigenetic control systems to gene regulation and plant development, examining paramutation, genomic imprinting and microRNA-based gene regulation mechanisms. Finally, it demonstrates the significance of epigenetic systems to viral defence and genome organisation.The volume is directed at researchers and professionals in plant molecular genetics, plant biochemistry and plant developmental biology. Review
	Mental Retardation and Developmental Delay: Genetic and Epigenetic Factors (Oxford Monographs on Medical Genetics) by: Moyra Smith M.D. publisher: Oxford University Press, USA, published: 2005-10-27 ISBN: 0195174321 sales rank: 720934 Product Description Recent advances in neuroscience and genetics have greatly expanded our understanding of the brain and of the etiological factors involved in developmental delay and mental retardation. At the same time, the human genome project has yielded a wealth of information on DNA sequencing, regulation of gene expression, epigenetics, and functional aspects of the genome, which newly propels investigation into the pathogenesis of mental retardation. This book makes readily available current knowledge on the subject and applies it to clinical medicine, providing information essential to neurologists, geneticists, physicians and pediatricians as they search for the causes of mental handicap in their patients. Introductory chapters cover normal and abnormal brain structure, neurogenesis, neuronal proliferation, and signal transduction. Latter chapters delve into discussions of both the environmental factors that may lead to neurocognitive deficits and the cytogenetic, biochemical and molecular defects specifically associated with mental retardation. One chapter reviews gene involvement in non-syndromic mental retardation, autism, and language deficits, as well as multifactorial and genetically complex inheritance. The text concludes with a clinically practical discussion of carrier detection, presymptomatic diagnosis, and treatment of various genetic diseases through enzyme therapy, substrate deprivation, and the use of hemapoietic stem cells. Review
	Chromatin Structure and Gene Expression (Frontiers in Molecular Biology) publisher: Oxford University Press, USA, published: 2001-02-15 ISBN: 019963890X sales rank: 1394767 Product Description Since publication of the first edition in 1995, there have been significant advances and understanding of chromatin structure and its relation to gene expression. These include a high-resolution structure of the nucleosome core, discovery of the enzymes and complexes that mediate histone acetylation and deacetylation, discovery of novel ATP-dependent chromatin remodeling complexes, new insights into nuclear organization and epigenetic silencing mechanisms. In light of these advances, Chromatin Structure and Gene Expression (2ed.) includes updated chapters and additional material that introduce new concepts in the process of gene regulation in chromatin. Review
	The Nucleus: Volume 2: Chromatin, Transcription, Envelope, Proteins, Dynamics, and Imaging (Methods in Molecular Biology) publisher: Humana Press, published: 2008-08-28 ISBN: 160327460X sales rank: 375663 Product Description Although our understanding of the structure and activities of the cell nucleus and of the nanomachines which it contains is increasing rapidly, much remains to be learned. The application and continuing development of the new, powerful biochemical and biophysical methodologies described here are essential in this quest. In The Nucleus, researchers from more than forty leading international laboratories describe state-of-the-art methods for isolating nuclei and their components and for studying their structure and activities, including some pathology-associated features. Volume 2: Chromatin, Transcription, Envelope, Proteins, Dynamics, and Imaging presents biophysical approaches to study the mechanical properties of nuclei, together with a comprehensive range of imaging methods. These include FISH, FRAP, FRET, molecular beacons, fluorescence correlation spectroscopy, single molecule tracking, and combing DNA for optical microscopy, recognition imaging for atomic force microscopy, and hybridisation, tomography, and spectroscopic imaging for electron microscopy. Written in the highly successful Methods in Molecular Biology? series format, chapters contain lists of necessary materials and reagents, readily reproducible protocols, and tips for troubleshooting and avoiding known pitfalls. The Nucleus, Volume 2: Chromatin, Transcription, Envelope, Proteins, Dynamics, and Imaging provides a comprehensive collection of the cutting-edge methods making a major contribution to understanding the nucleus and its nanostructure today. Review
	Schizophrenia: The Epigenetic Puzzle by: Irving I. & Shields, James Gottesman publisher: Cambridge 1984., published: 1984 sales rank: 5890419 Review
	Cancer Epigenetics by: Benjamin Tycko, Jean-pierre Issa publisher: Vch Verlagsgesellschaft Mbh, published: 2009-09-15 ISBN: 3527316426 Review
	Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life by: Eva; Lamb, Marion J. Jablonka publisher: The MIT Press, published: 2005 Review
	Epigenetics by: Soren Lovtrup publisher: John Wiley & Sons Ltd, published: 1974-01-01 ISBN: 0471549002 sales rank: 6225660 Review
	Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life [EVOLUTION IN 4 DIMENSIONS] publisher: MIT Press (MA), published: 2006-10-31 Review
	Nuclear Organization, Chromatin Structure, and Gene Expression publisher: Oxford University Press, USA, published: 1997-01-15 ISBN: 0198549237 sales rank: 7541363 Product Description This is one of the first books on emerging concepts about the role of the structure of chromatin, the organization of the genome, and the structure of the interphase nucleus in the control of gene expression in eukaryotes. The first section analyzes the relationship between gene expression and the dynamic chromatin structure at the nucleosome level. Section two looks into higher order chromatin structure in relation to transcription. The final section covers the molecular basis of epigenetic phenomena, like X-chromosome inactivation, starting from our knowledge of chromatin structure. Together these topics form the molecular basis for our understanding of cell differentiation, knowledge essential for the design of transgenic animals and plants and for gene therapy in humans. This book will be of direct interest to students and researchers in molecular and cell biology, providing them with essential tools for work on fundamental problems in transgenics and gene therapy. A number of human disorders may turn out to be caused by genetic or somatic errors at this levelof gene control, making this field of central importance. Review

Books on 'epigenetics|chromatin'