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| By: Ingvar Eidhammer, Inge Jonassen, William R. Taylor ISBN: 0470848391 Publisher: Wiley Release Date: 01 March, 2004 Bioscience book rank: 886031 | The book 'Protein Bioinformatics' tries to cover all aspects of proteins, from sequence to structure. This is of course a very wide field and the difficulty of the algorithms involved in this analysis increases from sequence to structure investigations. From the preface of the book one can read, that this is still not enough for the authors because additionally they are trying to write this book for a broad audience, for researchers and students.
<br />After reading this book I think it could be used by undergraduate students in Bioinformatics or related fields or as reference. It does not give deep and clear explanations but rather provides short summaries of articles. The good thing is after reading this book you know of the existence of these articles and can consult them to understand the working mechanism of the algorithms in detail.
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<br />There is certainly a lack in good books about proteins and especially about protein structure analysis which can partly filled by this book. This book gives good, basic coverage of the concepts important in understanding protein sequence and structure. <br /> <br />There are three major sections in this book: sequence, structure, and the relatinship between the two. The sequence section covers all the basics: dynamic programming for string matching, scoring matrices, trees and classification, and profiles of various sorts. The sequence discussion is a bit shorter, but goes over substructures, similarity searching and scoring, and kinds of structures and domains. The third section is even shorter and unites the two areas: predicting structure from sequence, with a good introduction to threading. <br /> <br />The book's strength is its breadth. It sacrifices depth to get that breadth, though. A few analytic techniques are sketched in the text or presented in psuedocode. Most often, however, a programmer will have a hard time gleaning enough detail from this to implement any of the algorithms described. <br /> <br />The authors aim at readers who already understand the significance of protein structure and who are comfortable with ideas like hydrogen bonding. Lots of programmers will have a hard time understanding why problems are important or what the driving phenomena are. Biologists won't be put off by an excessively mathematical treatment, but won't get a detailed understanding of the algorithms or mathematical foundations either. This book comes close to under-serving both kinds of reader. <br /> <br />This book is good for conceptual understanding of the algorithms, where implementable details don't matter, and gives good coverage to protein-specific issues. It's decidedly for someone who wants more than just the how-to of running BLAST or strucuture analysis tools. I think this book will help most if you want more understanding of what goes on inside the tools, or if you want an easy start to a deep and complex topic. Advanced readers may not like it, though - detail and real understanding just aren't there. I give this one four stars, but I had to round up to four. <br /> <br />//wiredwerid | |
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| By: Anna Tramontano, Arthur M. Lesk ISBN: 352731167X Publisher: Wiley-VCH Release Date: 20 March, 2006 Bioscience book rank: 482001 | ||
| By: J. Richardson ISBN: 0815333269 Publisher: Garland Science Release Date: 01 June, 1999 Bioscience book rank: 1176306 | ||
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| By: Mohammed Zaki, Chris Bystroff ISBN: 1588297527 Publisher: Humana Press Release Date: 12 September, 2007 Bioscience book rank: 1235472 | ||
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| By: Engelbert Buxbaum ISBN: 0387263527 Publisher: Springer Release Date: 18 September, 2007 Bioscience book rank: 800374 | Dr. Buxbaum presents the basic science of proteins and a survey of proteins categorized by function in a nicely illustrated volume, appropriate for introductory courses. Undergraduate biochemistry, chemistry and molecular biology courses; and graduate-level professional program courses could benefit from using the text as a one-stop presentation of essential material. Four sections cover protein structure, enzymes, special proteins, and membrane transport. There are brief problem sets following chapters, short bios of notable protein scientists, and references and an index provided in the appendices of the textbook. The size of the book is manageable for students. | |
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| By: Kenneth P. Murphy ISBN: 0896036820 Publisher: Humana Press Release Date: 15 March, 2001 Bioscience book rank: 1581592 | ||
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| By: Wolfgang B. Fischer ISBN: 0306484951 Publisher: Springer Release Date: 23 May, 2005 Bioscience book rank: 1518455 | ||
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| By: Igor F. Tsigelny ISBN: 096368177X Publisher: International University Line Release Date: 01 March, 2002 Bioscience book rank: 1421170 | ||
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| By: Arun K. Jagota ISBN: 0970029713 Publisher: Bioinformatics By the Bay Release Date: June, 2002 Bioscience book rank: 1766956 | ||
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| By: Ying Xu, Dong Xu, Jie Liang ISBN: 0387333193 Publisher: Springer Release Date: 15 December, 2006 Bioscience book rank: 1619690 | ||
Related books in this category:
bioinformatics, computational biology, sequence analysis, protein structure, data mining, biostatistics
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