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By: R. M. Twyman
ISBN: 1859962734
Publisher: BIOS Scientific Publ
Release Date: 24 September, 2004
Bioscience book rank: 536751
The illustrations were the best I have seen for a text explaining this subject. There are not alot of books about proteomics out there, but this is a must have for the introduction to this wonderful yet esoteric field. If you have no previous knowledge of biochemistry this book will be a very tough read. Enjoy.

This is a very good introduction and general review of the field of proteomics. It is excellent for those with little or no experience in the field. Because of the rapid changes occurring in this new science it does not include review of many of the useful software tools that have been developed.
By: A. Malcolm Campbell, Laurie J. Heyer
ISBN: 0805382194
Publisher: Benjamin Cummings
Release Date: 12 March, 2006
Bioscience book rank: 162343
This book follows a convoluted path to describe basic methodologies that could be taught in a much more straightforward manner. The authors get so mired down in the biology of specific applications of bioinformatic tools that the tool itself falls into the background. The poor layout of the book even makes it difficult to read. The main text of the book is interspersed with examples, "Math Minutes" and other text which are not properly set off from the main text. <br /> <br />The web links associated with the book are outdated and do not appear to be updated by the publisher to keep up with changes. If a web site is associated with a book, it should at the very least keep up with changes. In a quickly changing field such as bioinformatics these updates are absolutely critical. <br /> <br />The book is also overpriced given the low quality content and paperback binding. The figures are subpar with only purple and gray coloring. I would expect at least a few full color figures for a book at this price point. <br /> <br />Overall I would say that this book is not a useful tool for teaching bioinformatics or genomics.

This was a great textbook. The website was very helpful and I liked how the author did not waste paper/printing/money on images and half of the information was on the web. It was nice not carrying around a heavy text all semester, even if half my reading/work was done in front of a computer. A lot of information packed into this book. One sentence sometimes requires a lot of knowledge (thank goodness for my professor who explained it all). I would have to say, without a lecture, I would walk away from this text thinking I knew something but not knowing much at all. For an amature like me, I definitely need a lecture to go along with this text. Although some mistakes were found, a lot less than the first edition (so I'm told).

This book represents a breakthrough in textbook design. It starts with a 'case study' for a child visiting you the physician. You get the basic symptoms from the mother, then you are sent to the web to go attempt to establish a diagnosis. And you are not sent to some private web site, but to the Online Mendelian Inheitance in Man (OMIN) database of human diseases and genes, and to the National Center for Biotechnology Information. Immediately the student is exposed to a wealth of information far beyond what any book could provide. It's rare that you see a textbook that attempts to take the student into the real world. <br /> <br />Intermixed with the case studies is textual materials that provide the student with the basic background that they need. In addition there are almost random Math Minutes and Discovery Questions that direct the student into further depth of understanding. <br /> <br />If you are planning to teach this kind of class, you owe it to yourself to at least investigate this book before selecting a text.
By: Mark Pagel, Andrew Pomiankowski
ISBN: 0878936548
Publisher: Sinauer Associates Inc.,U.S.
Release Date: 10 December, 2007
Bioscience book rank: 607845
By: Werner Dubitzky, Martin Granzow, Daniel P. Berrar
ISBN: 0387475087
Publisher: Springer
Release Date: 19 December, 2006
Bioscience book rank: 191001
By: Daniel C. Liebler
ISBN: 0896039919
Publisher: Humana Press
Release Date: 15 December, 2001
Bioscience book rank: 698330
This very readable book provides an excellent overview of proteomics. It gives a survey of techniques, comparing them and explaining why and when they are used. This is not the place to learn any method in detail. But it is the only book I have seen that you can read cover to cover in a few days and get the big picture of the field. Some caveats: each chapter has only 3 or 4 references, and the book focuses on methods connected to mass spectrometry. But if you want a quick and pleasant introduction to methods for purifying and identifying proteins, including discussions of ICAT, protein complexes and post-translation modifications, I highly recommend this book.

There really are lots of good facts in this book. Somehow, though, they never come together to form a coherent whole.<p>Most chapters read like essays, meant to stand on their own. That means that many chapters repeat introductory material already covered, and remake points already made. Yes, I appreciate that silver staining does not properly represent the whole range of protein expression levels. I do not appreciate the need to stat that three or four times.<p>Despite its "Introduction" title, the author seems to forget what a novice will need to learn. For example, there's a discussion of isoelectric focussing for protein separation. That includes mention of the technique's history, and why it used to have reproducibility problems. I never did see an exact description of what the techique actually is or how it works, though. Likewise, the author describes a number of important software packages used in proteomics. There are no screen shots, though, comparisons of capabilities, details of usage, or even references for letting me find out more on my own.<p>When I got to the the end of this book, I wanted to go back and review a few points. Because of the generally poor organization, it was always a struggle to figure out just which discussion covered the topics I wanted. <p>Other books cover almost all of this title's content, and do so more clearly. I suggest that the interested reader keep on looking.
By: Richard J. Simpson
ISBN: 0879695544
Publisher: Cold Spring Harbor Laboratory Press
Release Date: 01 December, 2002
Bioscience book rank: 679253
To be fair this is a good and useful book, but at a higher price than the already excellent published (2002) laboratory proteomics by Westermeier and Naven, save your dollars. The latter goes for half the price and serves the same purpose with excellent illustrations and protocols.

This is a outstanding book, covering all aspects of sample preparation and experimental techniques involved in protein and peptide analysis by gels, liquid chromatography and mass spectrometry. Each chapter gives detailed protocols complete with tips, reagent lists, short tutorials (printed in blue colored information panels) and references. The protocols will work for you just as they are written and will give you a place to start in customizing and adapting them to your own circumstances (and you certainly will do that!). As with any fast moving field an updated second edition will be welcome around 2006, but by then, I'll be happy to replace my dog-eared copy for a fresh one (or maybe not, I don't really think a book as good as this will ever be obsolete). I recommend you buy the paperback edition, it will serve you well and save you some $$$.
By: Hubert Rehm
ISBN: 012088545X
Publisher: Academic Press
Release Date: 21 February, 2006
Bioscience book rank: 723340
In the chapter 2, a number of important pages (50-51, 54-55, 58-59, 62-63, 66-67, 70-71, 74-75, 78-79) is missed / left blank - apparently by the publisher's fault! This is really frustrating - a good book is ruined by a printing mishap!

I've found this book really very helpful. I'm essentially a geneticist/molecular biologist, but with this book I've been able to develop a multistep protocol for affinity purifying my protein of interest. The book is clear and concise, I would highly recommend it.
By: Elisa Eiseman
ISBN: 0833035274
Publisher: RAND Corporation
Release Date: January, 2004
Bioscience book rank: 741049
By: Steven H. Y. Wong
ISBN: 1594250464
Publisher: American Association for Clinical Chemistry,
Release Date: 01 May, 2006
Bioscience book rank: 465114
By: Rune Matthiesen
ISBN: 158829563X
Publisher: Humana Press
Release Date: 15 November, 2006
Bioscience book rank: 798857
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