mass spectrometry books

	Mass Spectrometry: Principles and Applications
	By: Edmond de Hoffmann, Vincent Stroobant ISBN: 0470033118 Publisher: Wiley-Interscience Release Date: 16 November, 2007 Bioscience book rank: 324744	This book was the text in my first course in mass spectrometry. The book is a good introduction to MS for advanced undergrads and graduate students. I felt the book was very helpful, it covers the multitude of ionization sources, mass analyzers, and even tandem MS. I give it a thumbs up.
	Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation
	By: J. Throck Watson, O. David Sparkman ISBN: 0470516348 Publisher: Wiley Release Date: 04 December, 2007 Bioscience book rank: 355597
	Mass Spectrometry: A Textbook
	By: Jürgen H. Gross ISBN: 3540407391 Publisher: Springer Release Date: 01 June, 2006 Bioscience book rank: 214593	Esse livro é excelente! Ele nos dá uma ótima noção dos termos utilizados em espectrometria de massas. Seu capítulo que aborda os isótopos exclarece de maneira objetiva a interpretação da distribuição isotópica em um espectro de massa. Esse obra traz a evolução dessa técnica abordando os diferentes métodos de ionização, as características dos diferentes tipos de analisadores como os de setores magnéticos, quadrupolos, armadilha de íons, tempo de vôo e até mesmo os de ressonância cinclotrônica. Descreve o funcionamento dos detectores e mostra também os diferentes espectros obtidos na análise dos diferentes compostos orgânicos. Eu recomendo! In the preface the reader is warned. If you know nothing about MS, you'll need to read it cover to cover, skipping the details of no interest to you. If you know some MS, just go to the chapter(s) that are interesting to you. <br /> <br />Used that way, it is an excellent book. Having some experience in GC, this book was to me a first choice because most books on GC-MS are pretty outdated. Although many books dealing with organic mass spectrometry (the present oeuvre is restricted to this field in a broad sense) have appeared over the years, since Beynons 1960 classic publication no single author has attempted to compile such a comprehensive treatise. The book comprises twelve chapters including basic principles (quasi-equilibrium theory, energy considerations--for example bond strengths, ionization energies, gas-phase basicities, etc., gas-phase ion chemistry, isotopes), instrumentation (ion separation in time-of-flight, sector-field, quadrupole, ion-trap, and ICR instruments), specifically electron ionization and in detail subsequent fragmentation of organic ions (specific processes, for example -cleavage or McLafferty rearrangement, are grouped together), alternative ionization techniques (chemical ionization, field ionization and desorption, fast atom bombardment and related techniques, MALDI, electrospray), and, in the closing chapter, so-called hyphenated methods (combinations of mass spectrometry with chromatographic methods and tandem mass spectrometry). Each chapter ends with an ample reference list comprising books and review articles and original publications. An appendix contains lists of elements and their isotopic composition, isotope patterns, characteristic fragments observed in electron-ionization spectra, and frequently encountered impurities. <br /> <br />Each chapter offers a detailed discussion with many illustrations facilitating understanding. Reference is always given to the original literature (as recent as 2003, as checks showed). The text is, however, occasionally somewhat verbose. In general the treatment of the various topics is of a thoroughness that it can be used also by advanced users of mass spectrometry for reference and deeper understanding. There are only few exceptions: thus the discussion of chemical ionization is essentially restricted to proton transfer, charge exchange, and electron capture whereas other reagent gases are just mentioned en passant. <br /> <br />Although many practical hints are interspersed in the text, a beginner in the field may be overawed by the wealth of information and ask, What should I do now? For example, in the over-detailed discussion of isotopes and accurate mass measurements there is no indication how to approach the list of elemental compositions obtained in daily practice (e.g. the nitrogen rule is discussed only many chapters later without any reference here). <br /> <br />H. Budzikiewicz
	The Expanding Role of Mass Spectrometry in Biotechnology, Second Edition
	By: Gary Siuzdak ISBN: 0974245127 Publisher: MCC Press Release Date: 31 January, 2006 Bioscience book rank: 97195	Easy to understand, give the useful information for who are not familiar with MS and if you are graduate student who taking MS class, you have to read this book. <br /> Whether you are a biochemist working in the field of biotechnology, or an analytical instrument engineer, Siuzdak's compact text makes for easy reading and a quick way to bone up on most of the MS techniques being used today in biotechnology. <br /> <br />The second edition is a big improvement--better illustrations and graphics (especially the ones for ESI-MUX, high throughput analysis and MALDI and Q-TOF.) Just about every technique and instrument type were covered except for a couple of rare ones I could think of. The range of chapters covers the mass analyzer types then covers the use of various analyzers in pharmacokinetics, molecular analysis, proteins, peptides, nucleic acids and carbohydrates, and high throughput screening. <br /> <br />If you are a professor of analytical chemistry, I would recommend Siuzdak's book for your class. It is well-written, easy to read and covers the subject well. This book would be a welcome desk reference for most scientists who use the services of a mass spectroscopist for their work. There are a few articles on mass spec analysis of steroids, its use in disease diagnosis and a good glossary in the back. Highly recommended as a good basic text.
	Fundamentals of Contemporary Mass Spectrometry (Wiley - Interscience Series on Mass Spectrometry)
	By: Chhabil Dass ISBN: 0471682292 Publisher: Wiley-Interscience Release Date: 20 April, 2007 Bioscience book rank: 613985
	*Liquid Chromatography Mass Spectrometry: An Introduction (Analytical Techniques in the Sciences (AnTs) )**
	By: Robert E. Ardrey ISBN: 0471498017 Publisher: Wiley Release Date: 11 April, 2003 Bioscience book rank: 396120	This book is very fundamental. For someone with little knowledge about HPLC-MS, this is the right book for him/her. IF you want to learn LC/MS, start with this book.
	Mass Spectrometry: A Foundation Course
	By: K. Downard ISBN: 0854046097 Publisher: Royal Society of Chemistry Release Date: 21 September, 2004 Bioscience book rank: 741946	This is an e-z to read book with all the basics of mass spectrometry and advanced applications. Unlike others you can actually understand why mass specs are built and operated they way there are, and there are plenty of good illustrations. There's a really good section on proteomics and medicial applications are also covered. I didn't know they took mass specs to mars! The history section was helpful to me in order to put the field in context. <br /> <br />I'd recommend it to any student of mass spec or someone else who wants to get a great overview. <br /> <br />Two thumbs up.
	Protein Sequencing and Identification Using Tandem Mass Spectrometry
	By: Michael Kinter, Nicholas E. Sherman ISBN: 0471322490 Publisher: Wiley-Interscience Release Date: 18 September, 2000 Bioscience book rank: 700100	Ao ler esse livro pude perceber que existe variadas técnicas que auxiliam na interpretação dos espectros de massas. A obra descreve os métodos de ionização e a formação dos íons moleculares e quasi-moleculares em cada um desses métodos. O livro tras a interpretação da distribuição de isótopos nas amostras, a identificação dos "parent ions", "base piks" e a distribuição das cargas durante a interpretação dos espectros. A interpretação de sequências de aminoácidos durante a análise de peptídios é rica em dicas, tabelas e exercícios resolvidos. De forma clara é possível entender a lógica por tras da formação das séries de íons A, B, C, X, Y e Z tão importantes durante a identificação da estrutura primária dos peptídeos. Se você pretende trabalhar com a identidficação de compostos de origem protéica utilizando espectrometria de massas, esse deverá ser seu livro de cabeceira! I'm not a bench chemist, but I needed a quick survey of how mass spectroscopy is used in handling proteins and other big biomolecules. This book was it. <br /> <br />Although brief, it is thorough and well-organized. The first two chapters are mostly an introduction. Chapter 1 states the problem being solved. The next chapter briefly introduces older technologies, including chemical techiques and 60s-80s mass spec technique. The next two chapters summarize modern mass spec hardware, then start to show how proteins behave in the environment inside the instrument. That gives the fundamentals of protein sequencing: how the molecules break down, and how the fragments help recreate the molecule. The authors go through a few examples in detail, starting from a mass spectrogram and moving forward to sequence. I was especially impressed by the examples that fail. Mass spec analysis is not a magic wand for producing sequences, it is a deductive process, and can not complete an analysis when clues are missing or ambiguous. <br /> <br />The next three chapters are not about mass spec directly. Instead, they discuss how samples are prepared for analysis. This includes the clearest, most informative description of gel electrophoresis that I've seen, along with features of gel chemistry that do or do not interfere with mass spec measurements. This includes a discussion of protein digests, enzymatically produced fragments, and their place in analysis. I would have liked a little more discussion about combining information from digests produced by different enzymes, but no book can cover everything. <br /> <br />The last three chapters extend the discussion of analysis, working upwards from fragments to complete protein sequences. The three chapters respectively address three topics: using standard internet databases for recognizing fragments of known proteins, using combinations of strategies to analyze novel proteins, and using mass spec to identify post-translational modifications. That last one suffers from brevity; perhaps it was only meant to define a problem that deserves a whole book of its own. <br /> <br />Despite its throughness, the authors resist the urge for boggling detail. They present detail up to the point needed for understanding the mechanism and meaning of their topics, then stop. Lots of other writing would benefit from that kind of restraint. <br /> <br />I came away from this book well-informed, and ready to address specific topics in greater detail. That was exactly what I wanted. I recommend this book very highly. <br /> <br />//wiredweird Michael Kinter has presented the topic in a scientific yet enjoyable format. I found the information to be extremely interesting and beneficial in my laboratory. Lets face it folks this isn't the easiest nor most interesting topic to write about. Job well done DR. Kinter. I only have one criticism, there should have been more photos and illustrations. Get your copies quick this will no doubt be on the NewYork times best seller list before long.
	Mass Spectrometry in Biophysics : Conformation and Dynamics of Biomolecules
	By: Igor A. Kaltashov, Stephen J. Eyles ISBN: 0471456020 Publisher: Wiley-Interscience Release Date: 21 April, 2005 Bioscience book rank: 798464
	Mass Spectrometry of Protein Interactions (Wiley - Interscience Series on Mass Spectrometry)
	By: Kevin Downard ISBN: 0471793736 Publisher: Wiley-Interscience Release Date: 10 August, 2007 Bioscience book rank: 832298