| |||||||||
| Bioscience book menu |
|
 | ||
| By: Michael W. Dong ISBN: 047172789X Publisher: Wiley-Interscience Release Date: 12 June, 2006 Bioscience book rank: 123415 | In this concise and very affordable book, Dr. Dong has compiled the most important concepts for anyone interested in the fundamentals of HPLC. He has also taken great care to provide clear illustrations to bring across these concepts, which, like many images, speak a thousand words. In a world inundated with almost too much information, it is very refreshing to have a text in hand that one can read through, understand, and put to use in a short amount of time. As a former research scientist turned Technical Sales Rep, I appreciate that I can put this book to work for me. Every chromatographer, new or experienced, needs to have this book on their shelf, or better yet, on top of the lab bench. HPLC has become one of the most widely applied chemical analytical techniques in the pharmaceutical industry. Dr Dong's book, Modern HPLC for Practicing Scientists, provides excellent source of information and knowledge for both beginners and highly experienced professionals who utilize this analytical tool. Chapter 1 presents an overview of chromatographic principles while the 2nd chapter deals with fundamental aspects of HPLC and considerations that enhance efficient separation. In chapter 3, Dr. Dong discusses the chromatographic column both from theoretical perspectives and applications. This is very valuable to practicing scientists. <br /> <br />In Chapter 4, the book provides a concise overview of HPLC instrumentation, operating principles as well as recent advances in instrumentation such as Waters Acquity UPLCTM (Chapter 11). A lot of information is provided on practical issues associated with the use of HPLC systems and the pictures and illustrations make their understanding much easier. <br /> <br />Chapter 5 provides a hands-on approach to HPLC analysis including mobile phase preparation and parameter optimization. This is a great chapter for a novel analyst who is often saddled with numerous options on the choice of HPLC parameters. Dr. Dong's attention to details makes it possible even for the novice chromatographer to undertake a full HPLC procedure with little or no supervision <br /> <br />Although Chapters 6 and 7 deal with applications in the pharmaceutical, food and environmental industries, the practicing scientist who this text is best suited for, would benefit more by integrating information from these chapters with the fundamental and practical concepts documented in the earlier chapters. <br /> <br />The inclusion of method development and regulatory issues with respect to HPLC techniques and applications in chapters 8 and 9 is particularly commendable. Industrial R & D scientists who are not only challenged to develop and optimize methods but also work within the constraints of regulatory agencies would find these chapters immensely rewarding. These chapters provide hands-on guidance for laboratory scientists in the pharmaceutical and other regulatory industries. <br /> <br />Chapter 10, dealing with troubleshooting is one of the special attributes of this book. This chapter provides quick fix approach to resolving some of the HPLC's often encountered problems. This chapter is bound to save some cost because more often than not, the HPLC analyst tend to vainly envisage and explore more catastrophic problems ignoring the simple remedies that are succinctly documented in Chapter 10. <br /> <br />Overall, Dr. Dong's book is very well written. Each aspect of the text is clearly and succinctly presented, making it easy to understand. The chapter on maintenance and troubleshooting guide (Chapter 11) should be a great asset. Dr. Dong has managed, in a very basic but meticulous manner, to produce an essential text for both the novice and experienced HPLC practitioner in the pharmaceutical industry. <br /> This is one of the best books on HPLC I have encountered. Gives an extremely thorough introduction to everything you should know inorder to get started and work confidently with this indispensible technology. Invaluable for the graduate student who wants to go hands on. | |
 | ||
| By: Lloyd R. Snyder, Joseph J. Kirkland, Joseph L. Glajch ISBN: 047100703X Publisher: Wiley-Interscience Release Date: 03 March, 1997 Bioscience book rank: 342546 | I find this book to be a valuable reference book on HPLC. I work extensively with HPLC and I can always rely on it to provide the in-depth explanations of what's going on. It covers all aspects of method development, form deciding where to start and figuring out what's going wrong, to finishing the method and validating it, although the validation chapter is just an overview. As of 2007, it's still relatively up to date, regarding new column technologies and latest practices.
<br />I really recommend this book, if it's your first time developing a method or if you're a seasoned professional, you will find many useful chapters in the book. This is a very useful reference to have if you work extensively on HPLC. I find its of more use to understand concepts ...there is a lot of information here. <p>Which means - if you are looking for a solution to a problem and you want to research separation theory - a great book. <p>If your looking for a quick fix to an HPLC problem - not as good. This is a detailed, extensive and well written text on HPLC Method development - wish there was more on validation here though. Rational Method development for HPLC is resented. Instruction of rational development of 3-solvent separation system is excellent. This book also has useful know-hows and tools in practical laboratory experiments, such as strength of hydrogen bonding of base silica and nomograph for estimation of "solvent strength" for reversed phase HPLC. | |
 | ||
| By: Yuri V. Kazakevich, Rosario LoBrutto ISBN: 0471681628 Publisher: Wiley-Interscience Release Date: 02 January, 2007 Bioscience book rank: 506045 | This book covers the fundamentals of HPLC separation with the inclusion of most recent advancements in the areas, such as column technologies, UPLC and LC-NMR. I found this book is really useful in a sense it provides overviews in almost every stages in the drug industry from discovery and process development to formulation, drug metabolism, and commercialization. This directly helps me to work more effectively with analytical chemists from other functional areas. The authors surely understand what are the practical challenges that a bench analytical chemist is facing everyday and provide a lot of usful strategies such as method development recipe in chapter 8 to tackle the problems. Overview, I view this book as a great reference for HPLC separation and problem solving manual for the analytical chemists in pharmaceutical industry. | |
 | ||
| By: Quanyun A. Xu, Lawrence A. Trissel ISBN: 085369723X Publisher: Pharmaceutical Press Release Date: 30 January, 2008 Bioscience book rank: 633544 | ||
 | ||
| By: Robert L. Cunico, Karen M. Gooding, Tim Wehr ISBN: 0966322908 Publisher: Bay Bioanalytical Laboratory, Inc. Release Date: June, 1998 Bioscience book rank: 777223 | This is without a doubt the most brilliant and poignant depiction of HPLC and CE of biomolecules in modern history. My extreme hyperactivity disorder usually means that I'm not able to sit still for such weighty topics--not without large amounts of abused Ritalin; but Cunico's work was so compelling and finely wrought that I found myself spellbound, even when drunk, even when driving in the backseat of a stolen car across the Mexican border at Tecate. I am not going to recommend drinking heavily and stealing cars. But I do recommend BASIC HPLC and CE OF BIOMOLECULES by Robert L. Cunico. By the way, I am extremely drunk right now. This is a book that should be on the desk of anyone who is involved in analytical development of biomolecules and biopharmaceuticals. The content is well organized and written in a format that is easy to grasp and understand. The content covers almost all the different modalities of HPLC analyses and applications and provides real life examples of the techniques. It includes innumerable suggestions on how best to develop a validatable HPLC method and analyze the data appropriately.<p>I would highly recommend this book to both new and old members of biotechnology, especially the developmental, analytical, and quality assurance groups where there is frequently a need to implement a solid reliable method for analyzing biomolecules in a more rational fashion. | |
 | ||
| By: Marie-Isabel Aguilar ISBN: 0896039773 Publisher: Humana Press Release Date: 15 December, 2003 Bioscience book rank: 579108 | ||
 | ||
| By: Stavros Kromidas ISBN: 352731377X Publisher: Wiley-VCH Release Date: 30 August, 2006 Bioscience book rank: 264017 | ||
 | ||
| By: Satinder Ahuja, Henrik Rasmussen ISBN: 0123705401 Publisher: Academic Press Release Date: 07 June, 2007 Bioscience book rank: 873649 | ||
 | ||
| By: Marvin McMaster ISBN: 0471754013 Publisher: Wiley Release Date: 18 December, 2006 Bioscience book rank: 135934 | I have recently been put in charge of an HPLC while having little experience in the field. This book was invaluable in developing my technique and was a gem as far as trouble-shooting goes (which I needed quite badly, I made a lot of mistakes at first). The only downside is that there hasn't been a new edition in almost 10 years, DAD and some of the processing have changed quite a lot and I would like to see that included if a future edition is made. This was the most useful and straightforward text I came across in my search for HPLC information. As a beginning user, I found the sections on troubleshooting, column aging diagnosis and healing, and method development to be invaluable in getting an HPLC system up and running in a new laboratory. I would highly recommend this reference tool to beginning users who do not have the opportunity to interact with an experienced HPLC user. One consideration when choosing this book is that it does not go into detail on any theory behind method development; however, it does offer sound advice on developing methods. | |
| By: Allen E. Ivey, Mary Bradford Ivey ISBN: 0495008400 Publisher: Wadsworth Publishing Release Date: 03 March, 2006 Bioscience book rank: 444600 | ||
Related books in this category:
proteomics, pharmacogenomics, mass spectrometry, electrophoresis, chromatography, HPLC, recombinant proteins, protein expression, protein purification, protein-protein protein-DNA/RNA interaction, phage display, drug discovery, biotechnology, pharmacology books
Main book index: all categories
|
| ||||||||