cell-cycle books

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Page 1 of 2004

The Immortal Life of Henrietta Lacks

by: Rebecca Skloot
publisher: Broadway, published: 2011-03-08
ASIN: 1400052181
EAN: 9781400052189
sales rank: 72
Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.

Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.

Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia—a land of wooden slave quarters, faith healings, and voodoo—to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.

Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.

Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?

Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

The Cell Cycle: Principles of Control (Primers in Biology) (Primers in Biology)

by: David O. Morgan
publisher: New Science Press, Ltd., published: 2006-09-06
ASIN: 0878935088
EAN: 9780878935086
sales rank: 762341
The Cell Cycle is an account of the mechanisms that control cell division, beginning with a description of the phases and main events of the cell cycle and the main model organisms in cell-cycle analysis, including Xenopus, Drosophila, and yeasts. Later chapters focus on the molecules and mechanisms of the cell-cycle control system, including the cyclin-dependent kinase family of protein kinases, the cyclins that activate them, and the signaling molecules that regulate them, and discuss cell-cycle control in development and the failure of controls in cancer.

The Cell Cycle: An Introduction

by: Andrew Murray
publisher: Oxford University Press, USA, published: 1993-09-23
ASIN: 0195095294
EAN: 9780195095296
sales rank: 562143
In the last decade there has been a revolution in our comprehension of how cells grow and divide. Results from experiments on yeast, embryos, and cultured mammalian cells have unified seemingly disparate viewpoints into a single set of principles for normal cellular reproduction in plants, animals and bacteria. Written by two leading participants in that revolution, The Cell Cycle provides the first thorough, authoritative account of the new philosophy of normal cellular reproduction and how it emerged. It is a vivid portrayal of the molecular logic of the cell: how the cell engine induces DNA replication and chromosome replication; how the integrity of genetic information is preserved; and how cell size and environmental signals regulate the cycle of growth and division. By describing important breakthroughs in their historical and experimental context, The Cell Cycle traces the development of the new vision of cell biology and shows its relevance to other areas of modern biology. It is the ideal introduction to the current understanding of cell growth and division for advanced undergraduate and graduate level cell biology courses.

Road Map for LC-MS, Antioxidant Activity, Total Phenolic Content, Toxicity and Anticancer Activity (Cell Cycle, Cell Death) Analysis for Natural Products

by: Muneer Abuismail
published: 2011-04-30
ASIN: B004YTMFP6
sales rank: 857965
Roadmap For Researchers
Full Test Procedures for Antioxidant Activity, Total Phenolic Content, Toxicity and Anticancer Activity (Cell Cycle, Cell Death) Analysis for olive leaf.
Full Data Analysis for Each Test.
Method Development for LC-MS Quantification of Phenolic, Flavonoidic and Triterpenic Compounds, Chromatographic Condetions are Provided.

Molecular and Cell Biology For Dummies

by: René Fester Kratz
publisher: Wiley Publishing, published: 2009-06-02
ASIN: 0470430664
EAN: 9780470430668
sales rank: 19852

Your hands-on study guide to the inner world of the cell
Need to get a handle on molecular and cell biology? This easy-to-understand guide explains the structure and function of the cell and how recombinant DNA technology is changing the face of science and medicine. You discover how fundamental principles and concepts relate to everyday life. Plus, you get plenty of study tips to improve your grades and score higher on exams!

Explore the world of the cell — take a tour inside the structure and function of cells and see how viruses attack and destroy them

Understand the stuff of life (molecules) — get up to speed on the structure of atoms, types of bonds, carbohydrates, proteins, DNA, RNA, and lipids

Watch as cells function and reproduce — see how cells communicate, obtain matter and energy, and copy themselves for growth, repair, and reproduction

Make sense of genetics — learn how parental cells organize their DNA during sexual reproduction and how scientists can predict inheritance patterns

Decode a cell's underlying programming — examine how DNA is read by cells, how it determines the traits of organisms, and how it's regulated by the cell

Harness the power of DNA — discover how scientists use molecular biology to explore genomes and solve current world problems
Open the book and find:

Easy-to-follow explanations of key topics

The life of a cell — what it needs to survive and reproduce

Why molecules are so vital to cells

Rules that govern cell behavior

Laws of thermodynamics and cellular work

The principles of Mendelian genetics

Useful Web sites

Important events in the development of DNA technology

Ten great ways to improve your biology grade

Cell and Molecular Biology: Concepts and Experiments (Karp, Cell and Molecular Biology)

by: Gerald Karp
publisher: Wiley, published: 2009-10-20
ASIN: 0470483377
EAN: 9780470483374
sales rank: 9531
Karp continues to help biologists make important connections between key concepts and experimentation. The sixth edition explores core concepts in considerable depth and presents experimental detail when it helps to explain and reinforce the concepts. The majority of discussions have been modified to reflect the latest changes in the field. The book also builds on its strong illustration program by opening each chapter with “VIP” art that serves as a visual summary for the chapter. Over 60 new micrographs and computer-derived images have been added to enhance the material. Biologists benefit from these changes as they build their skills in making the connection.

Cell Cycle - Materials and Methods (Springer Lab Manuals)

publisher: Springer, published: 1995-12-12
ASIN: 3540580662
EAN: 9783540580669
sales rank: 1167366
During their lifetime, especially when growing and dividing, cells go through various steps of the cell cycle. Knowledge of the individual steps of the cell cycle will help us understand the development of a variety of diseases better, including cancer, and also to design new drugs against it. New techniques for studying the molecular basis of these processes have recently been developed and are described in detail in this manual. A glossary helps the reader to cope with the complex cell cycle terminology.

Molecular Biology of the Cell, Fourth Edition

by: Bruce Alberts
publisher: Garland Science, published: 2002-03
ASIN: 0815332181
EAN: 9780815332183
sales rank: 32456
Molecular Biology of the Cell is the classic in-dept text reference in cell biology. By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

BRS Cell Biology and Histology (Board Review Series)

by: Leslie P. Gartner
publisher: Lippincott Williams & Wilkins, published: 2010-09-03
ASIN: 1608313212
EAN: 9781608313211
sales rank: 30609

BRS Cell Biology and Histology is an outline-format review for USMLE and course exams, with abundant electron micrographs and conceptual line drawings, high-yield Clinical Considerations boxes, review questions at the end of each chapter, and a comprehensive USMLE-format examination at the end of the book. This Sixth Edition features 60 new full-color photomicrographs and a new full-color design with colorized line drawings. Content and questions have been updated, new Clinical Considerations have been added, and Clinical Considerations have been better integrated into the content.

A companion website will offer the fully searchable text and an interactive question bank.

How Statin Drugs Really Lower Cholesterol: And Kill You One Cell at a Time

by: James B. and Hannah Yoseph
publisher: Hannah Yoseph, published: 2012-03-12
ASIN: 0615618170
EAN: 9780615618173
sales rank: 169777
The Yosephs have written the most stunning exposé. In simple language they reveal the science, the corruption and the enormous conspiracy it took to bring statins to market. As fast paced as a Mickey Spillane novel they report the research, the fraud and the facts like a detective in hot pursuit of a Nazi war criminal. Once picked up it cannot be put down until the reading is done. It is riveting. They have accomplished the impossible: they have made both complex science and medical history fascinating to read. What could not be done in an exposé they accomplished with almost unbelievable ease. It will change your paradigms about medicine forever. Read it!

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	The Immortal Life of Henrietta Lacks by: Rebecca Skloot publisher: Broadway, published: 2011-03-08 ASIN: 1400052181 EAN: 9781400052189 sales rank: 72 Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia—a land of wooden slave quarters, faith healings, and voodoo—to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.
	The Cell Cycle: Principles of Control (Primers in Biology) (Primers in Biology) by: David O. Morgan publisher: New Science Press, Ltd., published: 2006-09-06 ASIN: 0878935088 EAN: 9780878935086 sales rank: 762341 The Cell Cycle is an account of the mechanisms that control cell division, beginning with a description of the phases and main events of the cell cycle and the main model organisms in cell-cycle analysis, including Xenopus, Drosophila, and yeasts. Later chapters focus on the molecules and mechanisms of the cell-cycle control system, including the cyclin-dependent kinase family of protein kinases, the cyclins that activate them, and the signaling molecules that regulate them, and discuss cell-cycle control in development and the failure of controls in cancer.
	The Cell Cycle: An Introduction by: Andrew Murray publisher: Oxford University Press, USA, published: 1993-09-23 ASIN: 0195095294 EAN: 9780195095296 sales rank: 562143 In the last decade there has been a revolution in our comprehension of how cells grow and divide. Results from experiments on yeast, embryos, and cultured mammalian cells have unified seemingly disparate viewpoints into a single set of principles for normal cellular reproduction in plants, animals and bacteria. Written by two leading participants in that revolution, The Cell Cycle provides the first thorough, authoritative account of the new philosophy of normal cellular reproduction and how it emerged. It is a vivid portrayal of the molecular logic of the cell: how the cell engine induces DNA replication and chromosome replication; how the integrity of genetic information is preserved; and how cell size and environmental signals regulate the cycle of growth and division. By describing important breakthroughs in their historical and experimental context, The Cell Cycle traces the development of the new vision of cell biology and shows its relevance to other areas of modern biology. It is the ideal introduction to the current understanding of cell growth and division for advanced undergraduate and graduate level cell biology courses.
	Road Map for LC-MS, Antioxidant Activity, Total Phenolic Content, Toxicity and Anticancer Activity (Cell Cycle, Cell Death) Analysis for Natural Products by: Muneer Abuismail published: 2011-04-30 ASIN: B004YTMFP6 sales rank: 857965 Roadmap For Researchers Full Test Procedures for Antioxidant Activity, Total Phenolic Content, Toxicity and Anticancer Activity (Cell Cycle, Cell Death) Analysis for olive leaf. Full Data Analysis for Each Test. Method Development for LC-MS Quantification of Phenolic, Flavonoidic and Triterpenic Compounds, Chromatographic Condetions are Provided.
	Molecular and Cell Biology For Dummies by: René Fester Kratz publisher: Wiley Publishing, published: 2009-06-02 ASIN: 0470430664 EAN: 9780470430668 sales rank: 19852 Your hands-on study guide to the inner world of the cell Need to get a handle on molecular and cell biology? This easy-to-understand guide explains the structure and function of the cell and how recombinant DNA technology is changing the face of science and medicine. You discover how fundamental principles and concepts relate to everyday life. Plus, you get plenty of study tips to improve your grades and score higher on exams! Explore the world of the cell — take a tour inside the structure and function of cells and see how viruses attack and destroy them Understand the stuff of life (molecules) — get up to speed on the structure of atoms, types of bonds, carbohydrates, proteins, DNA, RNA, and lipids Watch as cells function and reproduce — see how cells communicate, obtain matter and energy, and copy themselves for growth, repair, and reproduction Make sense of genetics — learn how parental cells organize their DNA during sexual reproduction and how scientists can predict inheritance patterns Decode a cell's underlying programming — examine how DNA is read by cells, how it determines the traits of organisms, and how it's regulated by the cell Harness the power of DNA — discover how scientists use molecular biology to explore genomes and solve current world problems Open the book and find: Easy-to-follow explanations of key topics The life of a cell — what it needs to survive and reproduce Why molecules are so vital to cells Rules that govern cell behavior Laws of thermodynamics and cellular work The principles of Mendelian genetics Useful Web sites Important events in the development of DNA technology Ten great ways to improve your biology grade
	Cell and Molecular Biology: Concepts and Experiments (Karp, Cell and Molecular Biology) by: Gerald Karp publisher: Wiley, published: 2009-10-20 ASIN: 0470483377 EAN: 9780470483374 sales rank: 9531 Karp continues to help biologists make important connections between key concepts and experimentation. The sixth edition explores core concepts in considerable depth and presents experimental detail when it helps to explain and reinforce the concepts. The majority of discussions have been modified to reflect the latest changes in the field. The book also builds on its strong illustration program by opening each chapter with “VIP” art that serves as a visual summary for the chapter. Over 60 new micrographs and computer-derived images have been added to enhance the material. Biologists benefit from these changes as they build their skills in making the connection.
	Cell Cycle - Materials and Methods (Springer Lab Manuals) publisher: Springer, published: 1995-12-12 ASIN: 3540580662 EAN: 9783540580669 sales rank: 1167366 During their lifetime, especially when growing and dividing, cells go through various steps of the cell cycle. Knowledge of the individual steps of the cell cycle will help us understand the development of a variety of diseases better, including cancer, and also to design new drugs against it. New techniques for studying the molecular basis of these processes have recently been developed and are described in detail in this manual. A glossary helps the reader to cope with the complex cell cycle terminology.
	Molecular Biology of the Cell, Fourth Edition by: Bruce Alberts publisher: Garland Science, published: 2002-03 ASIN: 0815332181 EAN: 9780815332183 sales rank: 32456 Molecular Biology of the Cell is the classic in-dept text reference in cell biology. By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.
	BRS Cell Biology and Histology (Board Review Series) by: Leslie P. Gartner publisher: Lippincott Williams & Wilkins, published: 2010-09-03 ASIN: 1608313212 EAN: 9781608313211 sales rank: 30609 BRS Cell Biology and Histology is an outline-format review for USMLE and course exams, with abundant electron micrographs and conceptual line drawings, high-yield Clinical Considerations boxes, review questions at the end of each chapter, and a comprehensive USMLE-format examination at the end of the book. This Sixth Edition features 60 new full-color photomicrographs and a new full-color design with colorized line drawings. Content and questions have been updated, new Clinical Considerations have been added, and Clinical Considerations have been better integrated into the content. A companion website will offer the fully searchable text and an interactive question bank.
	How Statin Drugs Really Lower Cholesterol: And Kill You One Cell at a Time by: James B. and Hannah Yoseph publisher: Hannah Yoseph, published: 2012-03-12 ASIN: 0615618170 EAN: 9780615618173 sales rank: 169777 The Yosephs have written the most stunning exposé. In simple language they reveal the science, the corruption and the enormous conspiracy it took to bring statins to market. As fast paced as a Mickey Spillane novel they report the research, the fraud and the facts like a detective in hot pursuit of a Nazi war criminal. Once picked up it cannot be put down until the reading is done. It is riveting. They have accomplished the impossible: they have made both complex science and medical history fascinating to read. What could not be done in an exposé they accomplished with almost unbelievable ease. It will change your paradigms about medicine forever. Read it!